拉萨市农村0～5月龄儿童血红蛋白水平分析.docVIP

  拉萨市农村 0～5 月龄儿童血红蛋白水平分析# 康轶君，颜虹，李强，党少农，曾令霞，裴磊磊，张超** （西安交通大学医学院公共卫生系流行病与卫生统计教研室, 西安 710061） 5 10 15 20 25 30 摘要：目的：了解拉萨市农村 0～5 月龄儿童血红蛋白（Hb）水平和高海拔地区贫血患病状 况。方法：采用横断面研究设计与分层多阶段整群随机抽样获取样本。用 B-Hemoglobin 血 红蛋白仪，取儿童指末梢血 10ul 测量 Hb 含量。运用 CDC 法对 Hb 进行海拔调整，按照我 国小儿血液病会议的标准判断 0～5 月龄儿童贫血的界值，估计贫血患病率。结果：调查了 拉萨市农村 0～5 月龄儿童 99 名， Hb 的水平为 120.7±18.9g/L，协方差分析控制海拔因素 后，儿童在新生儿期的 Hb 水平（141.1±30.5g/L）明显高于儿童 1～3 月龄 Hb 水平 （117.2±16.7g/L）和 4～5 月龄 Hb 水平（120.2±15.6g/L）（P＜0.001 和 P=0.002）, 运用 CDC 法对 Hb 进行海拔调整后，儿童贫血患病率为 65.7%，男童（66.7%）略高于女童（64.1%） （P=0.793），儿童在新生儿期、1～3 月龄和 4～5 月龄贫血患病率分别为 88.9%、57.1%和 70.7%，3 个年龄段之间未发现统计学差异（P=0.123）。结论：拉萨市农村 0～5 月龄儿童 贫血患病率可能较高，用 CDC 法对新生儿 Hb 水平进行调整后可能高估了该人群贫血患病 率。高海拔地区婴儿贫血标准应引起重视。 关键词：血红蛋白；0～5 月龄儿童；拉萨农村 中图分类号：R174+6 Study on the status of Hemoglobin levels among children 0～ 5 months old in rural Lhasa KANG Yijun, YAN Hong, LI Qiang, DANG Shaonong, ZENG Lingxia, PEI Leilei, ZHANG Chao (Department of Epidemiology and Health Statistics,School of Public Health, Xian Jiaotong University College of Medicine, Xian 710061) Abstract: Objective: To study the hemoglobin status of children under the age of 0～ 5 months and the prevalence of anemia at High altitude. Methods: Cross-sectional study and random cluster sampling were used. Blood was collected on tip of finger and the level of hemoglobin was measured using B-Hemoglobin photometer.We adjusted the hemoglobin based on altitude using method of CDC and then estimated the prevalence of anemia. Anemia to determine the standards developed by the Conference in accordance with Chinas blood disease diagnostic criteria for anemia in infants. Results: In 2010, 99 infants of age 0～ 5 months living at 3608～ 3776 meters above sea level in rural Lhasa were examined. The findings indicated that the average hemoglobin was about 120.7 18.9g/L. Analysis of covriance indicated, after controlling the factor of altitude, 35 40 the mean of Hb level at newborn (141.1 30.5g/L) the highest than age at 1～ 3 months (117.2 16.7g/L) and 4～