e04.Cartilage Bone软骨和骨.ppt

组织胚胎学课件 七年制英文医学班专用 Chapter 4  Cartilage and Bone 1. Cartilage: organ=Cartilage tissue+perichondrium 1)????? structure of cartilage tissue ---cell: chondrocyte ---cartilage matrix ①???? chondrocyte: ---Structure: LM embedded in cartilage lacuna peripheral cells: --small and immature --single and flattened central cell: --large and mature, --round and in group of 2-8 cells --small and round nucleus --basophilic cytoplasm --EM: rich in RER and Golgi complex *isogenous group: several cells locates in one lacuna, which are derived from a single(same) parent cell ②???? Cartilage matrix ---ground substance: proteoglycan: --same to loose CT --there are more chondroitin sulfate distributed at the periphery of cartilage lacuna---called as cartilage capsule(basophilic) chondronectin water ---fiber: type and number of fiber depends on the type of cartilage 2) Classification: according to the fiber Hyaline cartilage: less collagenous fibril←type II collagen articular surface, rib cartilage, trachea and bronchi Fibrous cartilage: large amount of collagenous fiber bundles cells are small and less intervertebral disc, symphysis pubis Elastic cartilage: large amount of elastic fiber external ear, epiglottis 3) perichondrium two layers: ---out layer: contain more fiber-protection ---inner layer: more cells-osteoprogenitor cell(fusiform in shape) 4) growth of cartilage ---interstitial growth: inner chondrocyte proliferation→ produce fiber and matrix. immature cartilage ---appositional growth: osteoprogenitor cell→cartilage cell (chondrocyte) → produce fiber and matrix. growing and mature cartilage 2.Bone ---consists of bone tissue, periosteum and endosteum, bone marrow 1)????? Bone tissue ① Cells: a. osteoprogenitor cell: stem cell ---structure: fusiform, small ovoid nucleus slight basophilic cytoplasm exist in periosteum and endos