e10.Immune system免疫系统.ppt

组织胚胎学课件 七年制英文医学班专用  Chapter 10  Immune system 1. Components 1)????? Cells ① Lymphocyte: a. T-lymphocytes: cytotoxic T cell: Tc C- kill the tumor cell, virus infective cell and foreign cell helper T cell: Th C- promotes activity of BLC and Tc C suppressor T cell: Ts C –regulate the function of BLC and TC b. B-lymphocytes: become into plasma cell c. NK cell: counteract virus infective cell and tumor cell ②Plasma cell ③antigen presenting cell: a.?dendritic cell: Blood DC Langerhans cell interstitial cell veiled cell interdigitating cell b.macrophage: mononuclear phagocytic system ④other cells: granulated cell mast cell blood platelet blood-borne stem cell *Function: i.??????immunologic defence function ii.?????immune surveillance function iii.????immune homeostasis 2)???? Lymphoid tissue ---reticular T: reticular cell: stellate-shaped with processes to form network reticular fiber ---lymphocytes, macrophage, plasma cell and mast cell a. Diffuse LT: no clear boundary mainly consists of TLC postcapillary venules: -high endothelial venules -opening for LC enter LT from blood b. Lymphoid nodule: spherical or ovoid have clear boundaries mainly composed of BLC germinal center: stained pale * primary LN → secondary LN 3) Lymphoid organs a. Central lymphoid organs: thymus, bone marrow developed earlier blood-borne stem cell comes from yolk sac microenvironment → proliferation promoting send LC to PLD and LT two weeks before borne b. Peripheral lymphoid organs: lymph node, spleen and palatine tonsil developed later LC come from CLO cell proliferation need antigen stimulating- antigen dependent place for immune reactions 2.thymus Structure of thymus ---capsule: CT→interlobular septum ---cortex: dark-staining ---medulla: lighter-staining ---consists of thymic epithelial cell, thymic stromal cell( ma, eo,mc, fibroblast and myoid cell) and t