HIV_HCV合并感染的相互影响及抗病毒治疗研究进展.pdfVIP

传染病信息 2014年12月30日 第27卷 第6期 Infect Dis Info, Vol. 27, No. 6, December 30, 2014 333 · · HIV/HCV 合并感染 的相互影响及抗病毒治疗研究进展 冯理智，蔡卫平，胡凤玉 摘要] 和 具有相似的传播途径，主要为输血血制品、性接触、母婴垂直及静脉注射吸毒等，因此 合 [ HIV HCV / HIV/HCV 并感染率高。 和 在体内有复杂的相互作用，使合并感染者的病程变化多样，治疗难度加大。现将 合并感染 HIV HCV HIV/HCV 后病毒间相互作用机制及临床抗病毒治疗的研究进展综述如下。 [关键词] ；丙型肝炎病毒；治疗学 HIV [中国图书资料分类号] [文献标志码] [文章编号] R373.51 A 1007-8134(2014)06-0333-05 Research progress of interactions between HIV and HCV and antiviral therapy in co-infected patients FENG Li-zhi, CAI Wei-ping*, HU Feng-yu Department of Infectious Diseases, Guangzhou Eighth People s Hospital, Guangzhou, Guangdong 510060, China *Corresponding author, E-mail: caiwp@163.net [Abstract] HIV and HCV frequently coexist because of their similar routes of transmission. Both viruses are mainly transmitted by exposure to contaminated blood or blood products, sexual contact, mother-to-child transmission and intravenous drug use. HIV/ HCV co-infection rate is high. There are complex interations of HIV with HCV and multiple disease courses in the co-infected patients. So they are more difficult to be treated. The authors describe the progress of the interactions of HIV and HCV and antiretroviral treatment in HIV/HCV co-infected patients. [Ke