我院2009年抗感染药物不良反应报告分析.pdfVIP

1397 2010 年 第 12 卷 第 8 期(总第 82 期) 合理用药 我院2009年抗感染药物不良反应报告分析 江漫, 赵红 (解放军空军总医院药学部,北京 100042) 【摘要】目的:了解分析我院抗感染药物不良反应报告(ADR)的具体情况,促进临床合理用药。方法:应用“军队ADR监测系统”软件对 我院2009年收集的22例抗感染药物引起的ADR报告从多个角度进行分析。结果:22例ADR报告涉及的药品有11种,注射剂居首位;氨基糖 苷类(7例,31.82%)和林可霉素类(7例,31.82%)是引发ADR的主要抗感染药; 给药途径主要为静脉滴注;女性患者多于男性患者;临床表 现以皮肤及其附件损害最常见(37.5%),其次为消化系统(15.62%)和神经系统损害(15.62%)。结论:为确保临床用药安全,应加强ADR监 测、报告工作,并注意监管药品在医院各部门流经的各个环节。 【关键词】抗感染药物; 药品不良反应; 报告; 分析 【中图分类号】 R969.3 R978 【文献标识码】 A 【文章编号】1009-0959(2010)08-1397-02 Analysis of ADR Reports Induced by Anti-infective Drugs in Our Hospital in 2009 Jiang Man, Zhao Hong (Department of Pharmacy, Air Force General Hospital, Beijing 100042,China) ABSTRACT Objective: To investigate the occurrence of adverse drug reaction(ADR) in our hospital in order to promote the safety and rationality 【 】 of drug use in clinic.Methods:22 ADR cases induced by anti-infective drugs collected in our hospital in 2009 were classified and analyzed statistically by PLA ADR Monitoring System from several respects. Results:There were 11 kinds of drugs involved in 22 ADR cases, among which injections dominated the first, and aminoglycosides (7 cases, 31.82%) and lincomycins(7 cases, 31.82%) were the main ADR-inducing anti-infective drugs. Intravenous drip was the main route of administration. Female were more than male. The main clinical manifestations were the lesions of skin and appendages, followed by damages of digestive system and nervo