具有细支气管肺泡癌特征肺腺癌与其他类型腺癌的对比分析_英文_.pdf

Chinese-German Journal of Clinical Oncology January 2010, Vol. 9, No. 1, P13–P16 DOI 10.1007/s10330-009-0180-x Comparative analysis of lung cancer with features of bronchioloalveolar carcinoma and other types of adenocarcinoma* Leina Sun, Yan Guo, Zhongli Zhan, Baocun Sun, Na Dong, Ankang Gu, Huanling Luan Department of Pathology, Tianjin Medical Universit Cancer Institute and Hoapital, Tianjin Key Laboratory of Cancer Prevention; Tianjin Diagnosis and Therapy Cancer of Lung Cancer, Tianjin 300060, China Received: 29 October 2009 / Revised: 5 December 2009 / Accepted: 25 December 2009 © Springer-Verlag Berlin Heidelberg 2010 Abstract Objective: The aim of this study was to investigate the clinicopathologic and prognostic factors of the partial subtypes of lung adenocarcinoma, including pure bronchioloalveolar carcinoma (BAC), adenocarcinoma (AC) with BAC com- ponent and AC without BAC component. Methods: One hundred and six adenocarcinoma specimens which were followed up completely for 3 years, were obtained from 106 patients (45 men and 61 women) who underwent surgical resection for pathologically confirmed pulmonary adenocarcinoma in the Cancer Hospital of Tianjin Medical University, from June 2004 to December 2005. According to the recent 2004 World Health Organization (WHO) pathological classification criteria of lung cancer, lung adenocarcinomas were divided into three subgroups: pure BAC, AC with BAC component and AC without BAC component. The clinical data were retrospectively analyzed based on statistical methods. All data were analyzed using SPSS statistics software and Kaplan-Meier survival curves were constructed, meanwhile, we conducted a Log-rank test. Results: The statistical analysis showed that no significant ass