关于乳腺癌新辅助化疗前后声像图变化的意义的问题.docVIP

关于乳腺癌新辅助化疗前后声像图变化的意义的问题文发布者：来源：寻医问药网 关于乳腺癌新辅助化疗前后声像图变化的意义的原因,关于乳腺癌新辅助化疗前后声像图变化的意义的相关知识。 ???乳腺癌新辅助化疗前后声像图变化的意义 ???中华超声影像学杂志 2000年第8期第16卷 临床研究 ???作者：王艳滨 陈敏华 张晖 严昆 廖盛日 王天峰 林本耀 ???单位：王艳滨（100036 北京肿瘤医院超声科；现在华北煤炭医学院附属医院超声科）；陈敏华 张晖 严昆 廖盛日 王天峰 林本耀（100036 北京肿瘤医院超声科） ???关键词：超声检查;乳腺肿瘤;药物疗法 ??? 【摘要】 目的 对乳腺癌术前新辅助化疗后超声各指标的变化进行观察分析，旨在探讨超声对其疗效评价的意义。 方法 42例进行新辅助化疗的乳腺癌患者，于化疗前、化疗后、手术前分别对乳腺癌原发灶及腋窝淋巴结进行观察及分析。结果 42例患者新辅助化疗后超声检查显示，32例乳腺癌原发灶体积显著缩小；形态不规则者由化疗前3例增至化疗后31例；周边有强回声带者由化疗前16例降至化疗后4例；边界清晰者由15例增至化疗后37例；肿物内回声偏多者由化疗前2例增至化疗后27例；化疗前未见囊性变，化疗后3例发生囊性变；后方回声有改变者由34例降至化疗后9例；有29例原发灶内血流丰富程度降低或消失；Vmax、RI值降低(P＜0.05，P＜0.025)。共发现29枚肿大淋巴结，化疗后21枚缩小或消失；有7例淋巴结内可检测出血流信号，化疗后5例血流丰富程度降低。结论 乳腺癌新辅助化疗后，原发灶和腋窝淋巴结的二维图像及彩色多普勒的多项指标发生显著性变化，超声检查有助于对乳腺癌化疗疗效的评价。 ??? ??? The value of ultrasonography applied in assessment of pre-adjuvant therapy for breast cancer ??? WANG Yanbin，CHEN Minhua，ZHANG Hui ??? （Department of Ultrasonography, School of Oncology, Beijing Medical University, Beijing 100036, China） ??? 【Abstract】 Objective To investigate the value of ultrasonographical assessment in breast cancer by analyzing the change in sonographical data of 42 patients following primary medical therapy.Methods Altogether,two sets of ultrasonograp hic data (including that of primary tumor and axillary lymph nodes ) and clinical assessment were taken before and after medical therapy independently. All of the sonographical examinations were performed with the 6.0～9.0 MHz liner array probe. Results After treatment, ultrasonographic features of primary tumor were found change in largely proportion, which were reducing in volume, morphology irregularity, existence of surrounding halo, distinct boundary, increasing of internal echoes, rear echo, decreasing of color Doppler signals and reducing of value of Vmax and RI. Changes of axillary metastasis lymph nodes were found, such as reducing in volume, decreasing of color Doppler signals.Conclusions These changes of US futures above demonstrated were help to assessment the effectiven