循证医学与个体化医疗.pdfVIP

2009 6 7 6 Journal of Chinese Integrative edicine, June 2009, Vol.7, No.6 505 Editorial 刘建平 , 100029 : 21世纪临床医学强调 个体化医疗模式,这种模式的提出是基于人类基因组计划( 基因分型和 核苷酸 态性) 的发现以及新的医疗模式(生物心理社会环境精神),充分体现了以人为本的医疗理念,这与中医 药数千年来的个体化辨证论治有不谋而合之处循证医学时代对个体化医疗的理解和要求促进了对个体化 医疗的实践研究, 真正使外部研究证据医生 个人技能和经验与患者的价值观和偏爱有机结合,做出明智合 理的医疗决策本文论述了个体化医疗的含义以及中医的 个体化诊疗特征,就循证医学时代如何开展 个体 化诊疗和实践研究提出了建议 : 循证医学; 临床医疗模式; 个体化医学; 辨证论治 Liu JP. J Ch in I nteg r Med . 2009; 7( 6) : 505508. Received April 13, 2009; accepted April 24, 2009; published online June 15, 2009. Indexed/ abstracted in and full text linkout at Pub ed. Journal title in Pub ed: Zhong X i Yi J ie H e X ue B ao . Free full text ( HT L and PDF) is availableat www.jcimjournal. com. Forward linking and reference linking via CrossRef. DOI: 10.3736/ jci Open Access Evidencebased medicine and individualized healt h care Jianping LIU Center for EvidenceBased Chinese edicine, Beijing University of Chinese edicine, Beijing 100029, China Abstract: In 21st century, clinical medicine moves toward a model of individualized health care. The development of the individualized model is based onthe researchfindings ofhuman genomics project including genotype and single nucleotide polymorphisms ( SNPs), as well as the new health care model, that is, biologicalpsychologicalsocialenvironmentalspiritual. It reflects the idea of patientcentered care, and corresponds to the traditionalpractice of Chinese medicine, whichaddressedthe individualized therapy onthe basis of symptom pattern differentiation. However, the era of evidencebased medicine affords new meanings of individualized health care and promotes the research on the practice. The practice based on evidence would happen upon the integration of external research evidence, the expertise and experience of practitioners, and the value an