妊娠期糖尿病危险因素及血糖干预对妊娠结局的影响分析.docVIP

妊娠期糖尿病危险因素及血糖干预对妊娠结局的影响分析 雅安市中心血站 高文香 芦山县人民医院 汪能素 石棉县妇幼保健院 康克蓉 【摘要】目的 。方法 。结果=3.019）、妊娠年龄（OR=1.568）、高血红蛋白血症（OR=1.519）、月经周期紊乱（OR=2.018）、不良孕产史（OR=2.815）、糖尿病家族史（OR=4.948）均为GDM发病的危险因素。血糖控制不良组的妊娠期高血压疾病、羊水过多、酮症酸中毒、产后出血、剖宫产等并发症发生率均明显高于控制组（P0.05）；控制不良组的早产、巨大儿、新生儿窒息、新生儿低血糖、高胆红素血症等并发症发生率明显高于控制组（P0.05）。结论 GDM发病的危险因素，早发现、早诊断、早治疗GDM，重点控制妊娠期血糖水平，从而降低GDM对母婴妊娠结局的影响。 【关键字】Risk Factors of Gestational Diabetes Mellitus and Pregnancy Outcome Affected by Blood Sugar Intervention 【Abstract】Objective To explore the risk factors of estational diabetes mellitus (GDM), and study the effect of blood sugar intervention affecting pregnancy outcome. Methods With case-control study method, 140cases of GDM patients as case group and 140 cases without this disease as control group were collected. GDM cases were divided into good blood sugar control group (83 cases) and not good control group (57 cases) according to blood sugar control condition. The risk factors of GDM were analyzed and pregnancy outcome and complications were compared between good and not good control groups. Results Multiple factors Logistic Regression analysis result showed that overweight or obesity (OR=3.019), gestational age (OR=1.568), hyperhemoglobinemia (OR=1.519), menstrual cycle disorder (OR=2.018), adverse pregnancy history (OR=2.815), history of diabetes mellitus (OR=4.948). The complications incidence rates of pregnancy-induced hypertension syndrome, hydramnios, ketoacidosis, postpartum hemorrhage, uterine-incision delivery, premature delivery, large for date infant, neonatal asphyxia, hypoglycemia of newborn and hyperbilirubinemia in not good control group were much higher than not good control group (P0.05). Conclusion We should think highly of the risk factors of GDM, early discovering, early diagnosing and early treating GDM, especially controlling blood sugar level, thus cut down the effect of GDM to pregnancy outcome. 【Key words】Gestational diabetes mellitus; Pregnancy outcome; Complication; Risk factors;