2008级临床八年制2011年秋季《毒理学基础》试卷A.docVIP

南 方 医 科 大 学 公共卫生学院 2011学年（秋）季学期考试 2008年级预防医学（食品安全）本科班 《食品毒理学》试卷（A卷） 姓名 学号 专业 年级 考试时间: 2012.1.10 学时数：36 学生人数：91人 答卷时间： 14:30-16:30 组卷人: 刘云 题 型 单选题 正误题 多选题 问答题 合 计 满 分 50 40 10 0 100 Ⅰ. Multiple Choice Questions (Type A1, ONLY ONE answer is correct; please mark your answer by blackening A, B, C, D, or E on your answering sheet with a pencil; totally 50 questions, each scoring 1): 1. The three main specialized areas of toxicology is human toxicology, animal toxicology, and cellular toxicology in vitro toxicology, in vivo toxicology, and translational toxicology clinical toxicology, forensic toxicology, and environmental toxicology descriptive toxicology, mechanistic toxicology, and regulatory toxicology agricultural toxicology, ecotoxicology, occupational toxicology 2．In which of the following type of toxicological studies the investigated populations demonstrate “real-life exposures” to the suspected substances? A. In vivo studies B. In vitro studies C. Epidemiological studies D. Clinical exposure studies E. Accidental acute poisonings 3. The three R’s of humane animal use in toxicological research are A. rapid, real exposure, and repeat B. rapid, reduce, and refine C. reject, reduce, and replace D. refine, reduce, and replace E. refine, repeat, and rapid Toxicology is the studies on the biological effects on living organisms the biological effects on humans the adverse effects on living organisms the adverse effects on humans the adverse effects on mammalian animals 5．Inhalation of irritant gases (e.g., SO2, NH3) typically causes A. systemic toxicity B. local toxicity C. allergic reaction D. idiocyncratic reaction E. all of the above 6．Urinal levels of phenyl sulfate and phenyl glucuronide in workers are usually A. Biomarkers of exposure to benzene or phenol B. Biomarkers of effect of benzene or phenol exposure C. Biomarkers of susceptibility of workers to benzene or phenol