NIH-CAP 2015-06 Participating Companies.doc

NIH-CAP 2005-06 Participating Companies  21st Century Medicine, Inc. Rancho Cucamonga, CA Dean BarryTel: 909-466-8633Email: jdbarry@21CM.com 21st Century Medicine, Inc. has developed novel technologies for cryopreservation and long-term storage of biological tissue slices. Tissue slices are used pervasively during pharmaceutical drug discovery and development, however their use is problematic. Because these tissues can not currently be effectively stored, extensive on-site live animal preparations are required. 21st Century Medicine is currently validating cryopreserved neural, kidney, liver, and intestinal tissue for ADME/Tox testing applications.? Ready-to-use tissue slices configured for specific testing requirements will significantly increase throughput, reduce on-site testing costs, reduce variation, and further the potential for analytical standardization. Preservation systems for clinical applications are also under development. ABIOMED, Inc. Danvers, MA Robert StewartTel: 847-491-3280Email: rstewart@ ABIOMED, Inc. is a leading developer, manufacturer and marketer of medical products designed to assist or replace the pumping function of the failing heart. ABIOMED currently manufactures and sells the AB5000? Circulatory Support System and the BVS? 5000 Biventricular Support System for the temporary support of all patients with failing but potentially recoverable hearts.? In Europe, ABIOMED offers the Impella? Recover? minimally invasive cardiovascular support systems under CE Mark approval.? The Company’s AbioCor? Implantable Replacement Heart is the subject of an initial clinical trial being conducted under an Investigational Device Exemption from the United States Food and Drug Administration. Acme Express, Inc. Cleveland, OH Don ScipioneTel: 216-391-7400Email: dscipione@ Acme Express, Inc. develops healthcare staff scheduling software that cuts schedule-making costs by 80%, optimizes the schedule, and eliminates paper work. Doctors On