社区老年患者潜在性不适当用药问题调查与分析(赵欢).docVIP

社区老年患者潜在性不适当用药情况调查分析 赵欢*， 薛鹏2 吴新宝3包建民1 （1，天津大学 药物科学与技术学院 天津 300072；2，河北医科大学公共卫生学院社会医学与卫生事业管理教研室 石家庄050017；3，石家庄东里社区卫生服务站 石家庄 050051 ） 摘 要：目的：对社区老年非住院患者的潜在用药风险进行评估，探讨其影响因素，为开展社区老年药学服务提供参考。方法：以Beers 准则（2003 年版）为依据，对分层随机抽样的石家庄三个社区的416 例老年患者的用药潜在风险进行评价，确定其潜在性不适当用药的发生率及影响因子。结果：416例老年患者平均年龄72.7 岁，平均用药4.9种，平均罹患病3.5种，发生潜在性不适当用药的流行率为14.7％，影响老年人发生潜在性不适当用药的影响因子为用药数量，社区老年患者发生不良反应和服用潜在性不适当用药具有显著相关性。结论：beers准则在预测社区老年患者发生药物不良反应有重要的应用价值，应借鉴Beers 准则构建我国老年人安全用药指南；关注老年人潜在用药风险，强化药学服务。 关键词：beers 准则；社区老年患者；潜在性不适当用药；用药评估；不良反应； Prevalence of Potentially Inappropriate Medication in Community-Dwelling Elderly ZHAO Huan 1 XUE Peng2 WU Xin-bao3 BAO Jian-min1 (1.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072; 2. School of Public Health, Hebei Medical University, Shijiazhuang 050091; 3. Dongli Community Health Service, Shijiazhuang 050051, China) Abstract: Objective: To assess the potential risks of drug use in the community elderly non-hospitalized patients Methods: The Beers criteria (2003), based on stratified random sampling of 3 community Shijiazhuang 416 elderly patients to evaluate the potential risks of medication, inappropriate medication to determine the potential incidence and impact factor. Results:416 cases of elderly patients with an average age of 72.7 years, an average of 4.9 kinds of medication, an average of 3.5 kinds of suffering from disease, the occurrence of potentially inappropriate medication prevalence was 14.7%, affecting the occurrence of potentially inappropriate medication the elderly the impact factor of the number of medication . Conclusion:，older people should be concerned about potential drug risks, and strengthen pharmacy services, beers criteria for elderly patients in the community predict adverse drug reactions has important application value drawing on Beers criteria for elderly people in China to build safe medication guide. 中图分类号： R952；R699.3 ）Beers MH于1991年组织了美国老年病学、临床药理学和精神药理学等知名专家共同制订了老年潜在性不适当用药清单（Potentiall