apoptosis.pdfVIP

Apoptosis Apoptosis is also thought to play a role in the progression of many auto- immune diseases. For example, in the Phil Dash case of rheumatoid arthritis excessive Basic Medical Sciences, St.George’s, University of London proliferation of synovial cells is thought www.sgul.ac.uk/dept/immunology/~dash to be due in part to the resistance of these cells to apoptotic stimuli. In other Apoptosis, or programmed cell death, is a in the case of cancer cells mutations may cases poor regulation of apoptosis in T- normal component of the development and have occurred that prevent cells from lymphocytes can result in auto-reactive health of multicellular organisms. Cells undergoing apoptosis. In these cases there T-cells entering the circulation and die in response to a variety of stimuli and is no check on the cellular proliferation contributing to the onset of autoimmune during apoptosis they do so in a controlled, and consequently the disease can progress diseases. regulated fashion. This makes apoptosis to the formation of t