功能性消化不良患者胃排空功能及其症状的研究.docVIP

功能性消化不良患者胃排空功能及其症状的研究 　　作者：樊力红 吴静 袁敏翰 常青 　作者单位:：广州医学院第一附属医院消化内科 510120 　　【摘要】 目的：研究功能性消化不良(functional dyspepsia FD)患者的胃液体排空功能，探讨各种类型FD与胃液体排空功能的关系，及胃液体排空率与患者症状的相关性。方法： 按罗马Ⅱ诊断标准诊断的FD患者，分为运动障碍型(25例)，溃疡型(20例)，非特异型三组(12例)，设健康对照组(11例)。所有患者接受胃镜及腹部B超检查，排除上消化道及腹腔脏器的器质性病变，并检测Hp。然后通过B超用胃窦截面积法检测受试者30min、60min、90min及120min胃液体排空率，同时按统一标准对所有病人的消化不良症状进行评分。结果：(1)运动障碍型患者30min、60min、90min及非特异型30min胃排空率均低于对照组。(2)Hp阳性与阴性患者胃排空率及症状积分无差异。(3)FD患者症状积分与胃排空率无相关性。(4)男女性患者胃排空率无显著差异，但女性患者症状积分较男性患者高。结论：运动障碍型的FD患者有胃排空功能的缺陷，Hp感染与否不影响胃排空功能，FD患者症状轻重程度与胃排空功能并不相关，女性患者对症状的感受较敏感。 　　【关键词】功能性消化不良;胃排空功能 　　【Abstract】 Objective To investigate the gastric emptying abilities as well as the correlation between the emptying abilities and symptoms in patients with functional dyspepsia.Methods The patients were divided into dysˉmotility-like group，ulcer-like group and non-peculiar group according to their major symptoms.The degree of symptoms was evaluated in standard scoring system and the gastric emptying ability was tested by ultrasound.Results The postprandial emptying rates at30，60，90minutes in dysmotility-like group and30minutes in non-peculiar group were significantly lower compared with that of the control group.The gastric emptying function of the patients didnt correlate with their symptom scores.There was no significant difference in emptying abilities and symptom scores of the patients infected by Hp and non-infected by Hp.The symptom scores of women were significantly higher than that of men though their gastric emptying abilities were not different.Conclusion The gastric emptying abilities were deficient in patients classified as dysmotility-like，but the gastric emptying function of patients didnt correlate with their symptom scores.Hp didnt affect the gastric emptying function and the degree of the symptoms.Women were more sensitive to symptoms. 　　Key words:functional dyspepsia gastric emptying ability 　　临床上，功能性消化不良(FD)是指一组表现为上腹部不适、疼痛和上腹胀的症状，常在餐后加重，伴有早饱、食欲不振、恶心或呕吐等主要是以胃部不适为主的一组消化不良