丹参注射液联合骨髓干细胞移植治疗脑梗死肢体瘫痪临床与研究.pdfVIP

丹参注射液联合骨髓干细胞移植治疗脑梗死肢体瘫痪的临床研究 邓英光，张紫萍， 余卫 510620 510620 （广州市第十二人民医院，广东 广州 座机电话号码2200） 摘要：目的：探讨丹参注射液联合骨髓干细胞（MSC）移植治疗脑梗死肢体瘫痪的疗效 30 和安全性。方法： 例脑梗死肢体瘫痪患者随机分为治疗组和对照组。对照组丹参注射 液常规方法治疗，治疗组在丹参注射液常规基础上加用骨髓干细胞（MSC）治疗。两组 14d 28d NIHSS FCA , 病例于治疗前、治疗后 和 时分别进行 、 量表评定 并观察治疗期间 14d 28d 的不良反应。结果：丹参联合骨髓干细胞移植治疗后 及 与治疗前比较差异有统 计学意义 P 0.01 ，与丹参治疗组比较差异有统计学意义（P 0.05,P 0.01）。结论：丹参 注射液联合MSC治疗急性脑梗死安全可行。 关键词：丹参注射液；骨髓干细胞；脑梗死 Clinical efficacy of Salvia miltiorrhiza injection combined with Clinical efficacy of Salvia miltiorrhiza injection combined with CClliinniiccaall eeffffiiccaaccyy ooff SSaallvviiaa mmiillttiioorrrrhhiizzaa iinnjjeeccttiioonn ccoommbbiinneedd wwiitthh marrowstemcellsintreatmentofcerebralinfarction marrowstemcellsintreatmentofcerebralinfarction mmaarrrroowwsstteemmcceellllssiinnttrreeaattmmeennttooffcceerreebbrraalliinnffaarrccttiioonn DENG ZHANG Yu DENG ZHANG Yu DDEENNGGYing-guang ZZHHAANNGGZi-ping,YYuu Wei ， th （ the12 People’sHospitalofGuangzhou,Guangdong510620,China ） [Abstract] Objective: [Abstract] Objective: [[AAbbssttrraacctt]] OObbjjeeccttiivvee:: To explore the efficacy and safety of salvia miltionrrhiza injection combinedwithmarrowstemcellsinthetreatmentofcerebralinfarction. Methods: Methods: MMeetthhooddss:: A total of 30 patients with acute cerebral infarction were randomly divided into 2 groups: the treatment group and the control group. The control group was treated by Salvia miltiorrhiza injection; the treatment group was treated with salvia miltionrrhiza injection combined with marrow stem cells. The two groups were evaluated with The National Institutes of Health Stroke Scale NIHSS and The Functional Capacity Assessment FCA prior to the treatment 14 days and 28 days after treatment. The adverse effects during the treatment were observed. Results: Results: RReessuullttss:: There was a statistically significant difference between at 14 or 28 days after treatment and before in the treatment group P 0.01 and between th