5_HT_3受体拮抗剂的进展与临床应用评价.pdf

5- HT 3 受体拮抗剂的进展与临床应用评价 张石革, 陈瑞红, 宗 怡( 北京大学北京积水潭医院, 北京市 100035) R975+ 4 A 1672- 2124 ( 2004) 06- 0331- 05 目的: 5- HT3 受体拮抗剂的进展和临床应用进行进一步评价, 以期为临床医师和药师提供参考方法: 通过 国内 外近期文献的收集整理 5- HT3 受体拮抗剂进行分析与综述结果与结论: 5- HT 3 受体拮抗剂的问世, 使缓解由癌症化疗所 致的呕吐已不再成为难题, 但须遵循目前国内外有关呕吐处理若干意见, 达到治疗的规范化 5- HT3 受体拮抗剂; 呕吐; 外周神经; 评价 Advancement and Evaluation of the Use of 5- HT Receptor Antagonists 3 ZHANG Shige, CHEN Ruihong, ZONG Yi ( Beijing Jishuitan Hospital o Beijing University , Beijing 100035) ABSTRACT OBJECT IVE: To summarizes the aspect o clinical evaluation and research progress on 5- HT3 receptor antagonists, in order to provide re erence or clinical doctors and pharmacists. METHODS : The common and new 5- HT3 receptor antagonists were analyzed and discussed by the way o reviewing medical literatures in recent years at home and abroad. RESULTS CONCLUSION : The ounding o 5- HT3 receptor antagonists makes relieving o vomiting caused by chemotherapy or cancer easier . But some rules about treatment o vomiting at home and abroad must be obeyed, in order to achieve standardized treatment. KE WORDS 5- HT3 receptor antagonists; vomiting; peripheral nerve; evaluation ( Vomiting ) , , , , 2 , , , 6 ~ 1 2 5- HT3 , ( ) , , , ( ) ( ) ( ) ( ) , 1 [ 17] , . 1995, 87( 9) : 632. [ J] . 世界华人消化杂志, 2004, 12( 9) : 2 159 . [ 22] . [ J] . 中国感染控 [ 18] Soga SF, Diehl AM. Gut lora - based therapy in liver 制杂志, 2003, 2( 1) : 74 . disease? The liver cares about the gut [ J] . Hepatology, 2004 , [ 23] , , , 等.