MTS180c临床应用文献汇编.pdf

MTS ORTHOWAVE 180C 治疗皮肤创伤、糖尿病足溃疡、烧伤 文献汇编 体外冲击波疗法通过增加局部血流灌注和组织再生促进STZ 糖尿病大鼠模型的伤口愈合 Extracorporeal shock-wave therapy enhanced wound healing via increasing topical blood perfusion and tissue regeneration in a rat model of STZ-induced diabetes Yur-Ren Kuo, MD, PhD1,2; Chun-Ting Wang, BS1,2; Feng-Sheng Wang, PhD2; Yuan-Cheng Chiang, MD1; Ching- Jen Wang, MD3 1. Department of Plastic and Reconstructive Surgery, 2. Medical Research, and 3. Orthopedics, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan 摘要 ABSTRACT 体外冲击波治疗（ESWT）在促进慢性皮肤创伤的愈合有显著的 Extracorporeal shock-wave therapy (ESWT) has a 积极影响。然而，其根本的生物机制原理仍不是很清楚。本研 significant positive effect in accelerating chronic wound healing. However, the bio-mechanisms operating during 究旨在了解ESWT 增强糖尿病伤口愈合的作用原理。在链脲佐菌 ESWT of wounds remain unclear. This study investigated 素诱导的糖尿病动物模型上制造背侧皮肤缺损（面积，6x5 厘 the effectiveness of ESWT in the enhancement of 米）。五十只雄性Wistar 大鼠随机分为五组。I 组：包括非糖 diabetic wound healing. A dorsal skin defect (area, 6x5 尿病大鼠的对照；Ⅱ组：糖尿病对照组，糖尿病大鼠没有接受 cm) in a streptozotocin-induced diabetes rodent model was used. Fifty male Wistar rats were divided into five ESWT；Ⅲ组：糖尿病大鼠在第三天接受一次ESWT （