基于模糊膨胀模型的细胞核轮廓提取方法.pdf

计算机研究与发展 ISSN 1000-1 9!CN 11-1777!TP Journalof Com uter Research anddevelo ment 4 （）： ， p p 9 1 01 00 !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! 基于模糊膨胀模型的细胞核轮廓提取方法 胡 敏 平西建 丁益洪 （信息工程大学信息工程学院信息科学系 郑州 4 000 ） （ ） hhummin# Cell nucleus se mentation based on f uzz Growin snake g y g ， ， ~u Min Pin Xiian anddin Yihon g j g g （ ， ， ， De artment o In ormation science Institute o In ormation en ineerin In ormation en ineerin Unioersit Zhen zhou P f f f f g g f g g y g 4 000 ） Abstract In this a er an automated cellnucleusse mentation method is ro osedbasedon a novel fuzz p p g p p y roWin snakemodelfor color cell ima esfrom eso ha eal smears. after estimatin theelli se arameters g g g p g g p p ， for each cell nucleus the ima e oint is ma ed into several fuzz domains Which measure tinctorial g p pp y uniformit and ositional roximit of the ixel tothenucleus. based on thesefuzz measures，a roWin y p p y p y g g active contour model is develo ed to track the nucleus boundar . To hel the model overcome localp y p ， minimum aself-ada tive roWin ener isaddedtoinflatethecontouruntilitex andsoutof thenucleus. p g g gy p Theutilization of elli seestimation ivesthemodelt