EMGCposter(KSC).ppt

* Background The incidence of early gastric cancer EGC has been increasing in Korea with favorable treatment results. Multiple early gastric cancer MEGC was reported to be 5.6%-17% of all EGC and overlooking the accessory lesions preoperatively or intraoperatively will adversely influence the overall treatment results of EGC Definition of MEGC according to Moertel et al To evaluate the prevalence, clinicopathologic features , and prognosis of MEGC patients Total of 1264 EGC patients Jan 1987- Dec 1997 56 patients with multiple lesions 4.4% All the patients received radical total or subtotal gastrectomy with LN dissection Follow up to June 2002 Parameter MEGC n 56 EGC n 1208 P value Gender 0.042 Male 43 76.8 768 63.6 Female 13 23.2 440 36.4 Mean age yrs 57.2 53.7 0.024 Lesion size mean mm 24 25 NS Location NS Upper 1/3 5 8.9 159 13.2 Middle 1/3 28 50.0 552 45.7 Lower 1/3 23 41.1 497 41.1 Macroscopic type 0.001 Elevated 19 33.9 191 15.8 Flat 3 5.4 153 12.7 Depressed 34 60.7 864 71.5 Depth of invasion NS Mucosa 26 46.4 635 52.6 Submucosa 30 53.6 573 47.4 Histologic type 0.013 Differentiated 35 62.5 551 45.6 Undifferentiated 21 37.5 657 54.4 Gastric resection NS Total 12 21.4 153 12.7 Subtotal 44 78.6 1055 87.3 LN dissection 0.010 D1 5 8.9 34 2.8 D2 or more 51 91.1 1174 97.2 LN metastasis NS Negative 49 87.5 1059 87.7 Positive 7 12.5 149 12.3 Recurrence 2 3.6 60 4.9 NS The number in parentheses are percentage. P .05 was considered significant. Clinical Study of Synchronous Multiple Early Gastric Cancer Chen J, Cheong JH, Kim J, Hyung WJ, Choi SH, Noh SH Department of Surgery, Yonsei University College of Medicine The incidence of MEGC was 4.4%in our series Male elder patients were predominant MEGC solitary EGC had the same prognosis Recommended evaluate the whole stomach before and during the oper