B型钠尿肽和CA125联合检测在呼吸困难鉴别诊断中的临床价值.pdf

Int J Lab Med May Vol No B CA B BNP CA BN PCA BNP CA BNP CA P BNP CA BNPCA P BNP CA P BNP CA B DOI issn A j Combined detection of BNP and CA for the differential diagnosis of dyspnea L i X irong Zhang X iaohua L i Chunlan Y ang M e iy an A f f iliate d M aoming TCM H osp ital of Guangz hou Univ e rs ity of TCM M aoming Guang dong China Abstract Objective T o ex plore the combined detection of B type natriuretic peptide BNP and glycosylated antigen CA in diff erential diagnosis of dy spnea Methods BNP and CA w ere detected and compared among cases w ith cardiac dy spnea cases w ith pulmonary dy spnea and healthy subjects Results BNP and CA levels of dy spnea patients w ere higher than healthy subjects and those of cardiac dy spnea patients w ere higher than pulmonary dy spnea patients P With the ag g ravation of heart failure BN P and CA levels g radually increased Combined detection of BNP and CA w ere w ith higher diag nostic sensitivity and specificity P Af ter treatment BN P and CA levels significantly decreased P Conclusion Combined detection of BNP and CA could be w ith high specificity and sensitivity helpf ul for identifying cardiac or pulmonary dy spnea and dynamic observation of the disease Key words Btype natriuretic peptide lycosylated antigen dy spnea g B BNP CA P 1 2 mL 1 r min min Centa