静电纺丝制备壳聚糖聚己内酯血管支架及表征.pdfVIP

28 1 2 2011 Acta Mater iae Comp ositae Sin ica Vol28 No1 February 2011 : 1000- 3851( 2011)01- 0104- 05 / 1 2 2 1 * 3 * 1 杨文静 , 付 静 , 何 磊 , 王 婷 , 王大新 , 何农跃 ( 1. , 210096; 2. , 210096; 3. , 225001, China) : (CS) ( PCL) , CS/ PCL SEM , ( EPCs), SEM : 400 n ; CS PCL 0.5 , CS/PCL 31.64%, - ; EPCs CS/ PCL 95. 1%, CS/PCL : ; ; ; ; : R318.08 : A Preparation and characterization of chitosan/ polycaprolactone vascular scaffolds by electrospinning 1 2 2 1 * 3 * 1 YANG Wenjing , FU Jing , HE Lei , WANG Ting , WANG Daxin , HE Nongyue ( 1. School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China; 2. School of Public Health Southeast, Southeast University, Nanjing 210096, China; 3. Clinical Medical Colleges, Yangzhou University, Yangzhou 225001, China) Abstract: The chitosan/polycaprolactone(CS/PCL) vascular scaffolds were prepared by electrospinning in order to co bine the advantage of chitosan( CS) and polycaprolactone(PCL) into the vascular scaffolds. The obtained CS/ PCL vascular scaffolds were characterized by SEM and electronic universal testing achine. The endothelial progenitor cells( EPCs) were i planted in the scaffolds with various ass ratios of CS to PCL. The vascular scaffolds were exa ined by adhesion rate in different culturing ti es and the cells breeding was observed. The obtained CS/PCL vascular scaffolds show porous, nanostructured surfaces, si ilar to the natural extracellular