《Semiquantitative Study of the EDCNHS Activation of Acid Terminal》.pdf

pubs.acs.org/Langmuir © 2009 American Chemical Society Semiquantitative Study of the EDC/NHS Activation of Acid Terminal Groups at Modified Porous Silicon Surfaces S. Sam,†,‡,§ L. Touahir,† J. Salvador Andresa,† P. Allongue,† J.-N. Chazalviel,† A. C. Gouget-Laemmel,† C. Henry de Villeneuve,† A. Moraillon,† F. Ozanam,*,† N. Gabouze,‡ and S. Djebbar§ † ‡ Physique de la Matiere Condensee, Ecole Polytechnique, CNRS, 91128 Palaiseau, France, UDTS, 2 bd Frantz Fanon, BP 399, Alger-Gare, Algiers, Algeria, and § Laboratoire d’hydrometallurgie et chimie inorganique moleculaire, Faculte de Chimie, USTHB, BP 32 El Alia, 16111 Bab-Ezzouar, Algiers, Algeria Received June 19, 2009 Infrared spectroscopy is used to investigate the transformation of carboxyl-terminated alkyl chains immobilized on a surface into succinimidyl ester-terminated chains by reaction with an aqueous solution of N-ethyl-N0 -(3- (dimethylamino)propyl)carbodiimide (EDC) and N-hydroxysuccinimide (NHS). The acid chains are covalently grafted at the surface of hydrogenated porous silicon whose large specific surface area allows for assessing t