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《Anthony Atala Printing a human kidney》.pdf
Anthony Atala: Printing a human kidney
Theres actually a major health crisis today in terms of the shortage of organs. The fact is that
were living longer. Medicine has done a much better job of making us live longer, and the
problem is, as we age, our organs tend to fail more, and so currently there are not enough organs
to go around. In fact, in the last 10 years, the number of patients requiring an organ has doubled,
while in the same time, the actual number of transplants has barely gone up. So this is now a
public health crisis.
So thats where this field comes in that we call the field of regenerative medicine. It really
involves many different areas. You can use, actually, scaffolds, biomaterials -- theyre like the
piece of your blouse or your shirt -- but specific materials you can actually implant in patients and
they will do well and help you regenerate. Or we can use cells alone, either your very own cells or
different stem cell populations. Or we can use both. We can use, actually, biomater ials and the
cells together. And thats where the field is today.
But its actually not a new field. Interestingly, this is a book that was published back in 1938. Its
titled The Culture of Organs. The first author, Alexis Carrel, a Nobel Prize winner . He actually
devised some of the same technologies used today for suturing blood vessels, and some of the
blood vessel grafts we use today were actually designed by Alexis. But I want you to note his
co-author: Charles Lindbergh. Thats the same Charles L indbergh who actually spent the rest of
his life working with Alexis at the Rockefeller Institute in New York in the area of the culture of
organs.
So if the fields been around for so long, why so few clinical adv
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