《Relationship between brachial-ankle pulse wave velocity and metabolic syndrome components in a Chinese population》.pdf

Availableonlineatwww．jbr-pub．org OpenAccessatPubMedCentral JBR TheJoumalofBiomedicalResearch，2014，28(4)：262—268 ResearchPaper Relationshipbetweenbrachial-a·nklepulsewavevelocityand metabolicsyndromecomponentsinaChinesepopulation FangZhou△ HaifengZhang，WenmingYao△ ， ， HongbinMei，DongjieXu，YanhuiSheng，RongYang， XiangqingKong，LianshengWang，JiangangZou，ZhijianYang圆，XinliLi圆 DepartmentofCardiology,theF tAffiliatedHospitalofN ngMedicalUniversity,Nanjing210029,China． Received11October2013，Revised02December2013，Accepted16M arch2014，Epub06June2014 Abstract Thepurposeofthisstudywastoassesstherelationshipbetweenarterialstiffness，asmeasuredbybrachial-ankle pulsewavevelocity(baPW_V)，andthepresenceofthemetabolicsyndrome(MS)inaChinesepopulation．A total of4．445subiectswereenrolled．TheprevalenceofMSinourstudypopulationwas21．7％．17．2％and25．6％ forhtegeneralpopulation，malesnadfemales，respectively．Wi廿1adjustmentsofrage，gender，cigarettesmoking， heartrate，total cholesterol，1ow—densitylipoprotein(LDL)cholesterol，andtheuseofanti—hypertensivedrug，the stepwiseregression analysisshowedthatbaPW V hadasignificantrelationshipwithcomponentsofM S， includingsystolicbloodpressure(P 0．001)，diastolicbloodpressure(P0．oo1)，glucose(P0．oo1)，high— densitylipoprotein(HDL)cholesterol(P=0．04)，andtriglycerides(P0．001)，butnorelationshipwith waistcircumference(P =0．25)．WithanincreaseinthenumberoftheMScomponents，baPWV increased significantlybothinwomenandmen．ThisstudyindicatedthattheM Sisindeedariskfactorforarterial stiffness．M onitoringofbaPvV inpatientswi廿1MSmayhelpinidentifyingpersonsathigh15skforcradiovascular disease． Keywords：arterial stiffness，brachial—anklepulsewavevelocity，metabolicsyndrome