Facile fabrication of bactericidal and antifouling switchable chitosan wound dressing through a ‘click’-type interfacial reaction》.pdf

Colloids and Surfaces B: Biointerfaces 136 (2015) 7–13 Contents lists available at ScienceDirect Colloids and Surfaces B: Biointerfaces j o u r n a l h o me p a g e : w w w. elsev /locate/cols urfb Facile fabrication of bactericidal and antifouling switchable chitosan wound dressing through a ‘click’-type interfacial reaction Xianghong Wang a,b , Shuaishuai Yuan b , Yu Guo c , Dean Shi a,∗ , Tao Jiang a , Shunjie Yan b , Jiao Ma b , Hengchong Shi b , Shifang Luan b,∗ , Jinghua Yin b,∗ a Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Collaborative Innovation Centerfor Advanced Organic Chemical Materials, Faculty of Materials Science and Engineering, Hubei University, Wuhan 430062, PR China b State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China c Jilin Province People’s Hospital, Changchun 130021, PR China a r t i c l e i n f o a b s t r a c t Article history: A facile approach to functionalize chitosan (CS) non-woven surface with the bactericidal and antifouling Received 8 June 2015 switchable moieties is presented. Azlactone-cationic carboxybetaine ester copolymer was firstly pre- Received in revised form 22 August 2015 pared, then chemically attached onto CS non-woven surface through the fast and efficient ‘click’-type Accepted 27 August 2015 interfacial reaction between CS primary amines and azlactone moieties. The CS non-woven surface func- tionalized with c