Gelatin-bioactive glass composites scaffolds with controlled macroporosity》.pdf

Chemical Engineering Journal 256 (2014) 9–13 Contents lists available at ScienceDirect Chemical Engineering Journal journal homepage: www.else /locate/cej Short communication Gelatin-bioactive glass composites scaffolds with controlled macroporosity Joséphine Lacroix, Edouard Jallot, Jonathan Lao ⇑ Clermont Université, Université Blaise Pascal, CNRS/IN2P3, Laboratoire de Physique Corpusculaire, BP 80026, 63171 Aubière Cedex, France h i g h l i g h t s Highly bioactive glass particles have been dispersed in a gelatin matrix. Composite scaffolds with controlled and 90% opened porosity are obtained at RTP. They are as bioactive as pure bioactive glass, but own higher compressive strengths. a r t i c l e i n f o a b s t r a c t Article history: Scaffolding materials are often needed for bone regeneration: their role is to act as temporary templates Received 29 November 2013 for the reconstruction of bone tissues either in situ or in the laboratory. Suitable properties for such scaf- Received in revised form 5 June 2014 folds are bioactivity and mechanical toughness, which can both be combined in composite matrices Accepted 6 June 2014 based on bioceramics and biopolymers. Among possible combinations, bioactive glasses possess unique Available online 19 June 2014 bone-bonding ability compared to other bioceramics, while gelatin is a biocompatible polymer naturally derived from collagen. Here we report the synthesis of bioac