Intramolecular fluorescence resonance energy transfer in a novel PDI–BODIPY dendritic structure Synthesis, Hg2+ sensor and living cell imaging》.pdf

Sensors and Actuators B 219 (2015) 57–64 Contents lists available at ScienceDirect Sensors and Actuators B: Chemical j o u r n a l h o m e p a ge : w w w. elsev /locate/snb Intramolecular fluorescence resonance energy transfer in a novel PDI–BODIPY dendritic structure: Synthesis, Hg2+ sensor and living cell imaging Huan-ren Cheng, Ying Qian ∗ School of Chemistry and Chemical Engineering, Southeast University, Nanjing, Jiangsu 211189, China a r t i c l e i n f o a b s t r a c t Article history: A novel intramolecular fluorescence resonance energy transfer (FRET) and photo-induced electron trans- Received 12 March 2015 fer (PET) based dendritic compound PDI–BODIPY has been developed: Tetra-boron-dipyrrin (BODIPY) Received in revised form 23 April 2015 attached perylene bisimide by click chemistry. Compound PDI–BODIPY as a fluorescence probe for rapid, Accepted 26 April 2015 selective, and sensitive determination of Hg(II) ions has 98% of high energy transfer efficiency. The dis- Available online 19 May 2015 2+ −12 sociation constant (Kd ) of the probe PDI–BODIPY with Hg is 6.67 × 10 M and the detection limit estimated from the titration results was 2 × 10−8 M. Moreover, the imaging of Hg(II) ions in Hela cells Keywords: further certified the potential value of the probe. Perylene diimide