Investigation of factors affecting hypothermic pelvic tissue cooling using bio-heat simulation based on MRI-segmented anatomic models》.pdf

c o m p u t e r m e t h o d s a n d p r o g r a m s i n b i o m e d i c i n e 1 2 2 ( 2 0 1 5 ) 76–88 j o u r n a l h o me p a g e : w w w. intl.e /journals/c mpb Investigation of factors affecting hypothermic pelvic tissue cooling using bio-heat simulation based on MRI-segmented anatomic models a b a c Yuting Lin , Wei-Ching Lin , Peter T. Fwu , Tzu-Ching Shih , Lee-Ren Yeh d, Min-Ying Su a, Jeon-Hor Chen a,d,∗ a Tu and Yuen Center for Functional Onco-Imaging of Department of Radiological Sciences, University of California, Irvine, CA 92697, USA b Department of Radiology, China Medical University Hospital, Taichung 40402, Taiwan c Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung 40402, Taiwan d Department of Radiology, E-Da Hospital and I-Shou University, Kaohsiung 82445, Taiwan a r t i c l e i n f o a b s t r a c t Article history: This study applied a simulation method to map the temperature distribution based on Received 13 March 2015 magnetic resonance imaging (MRI) of individual patients, and investigated the influence Received in revised form 8 June 2015 of different pelvic tissue types as well as the choice of thermal property parameters on Accepted 3 July 2015 the efficiency of endorectal cooling balloon (ECB). MR images of four subjects with differ- ent prostate sizes and pelvic tissue compositions, including fatty tissue and venous plexus, Keywords: were analyzed. The MR images acquired using endorectal coil provided a realistic geometry Endorectal coolin