克劳斯·尼尔森-布鲁氏菌病诊疗过程中被忽视的要点·第二届兽医大会专题.pdf

Brucellosis The forgotten and under-diagnosed disease Klaus. H. Nielsen and Wei Ling Yu Brucellosis – Introduction • 8个陆地物种的布鲁氏菌 • 8 terrestrial species of Brucella • *牛种-牛 *B. abortus – cattle *羊种-小型反刍动物 *B. melitensis – small ruminants *猪种-猪 *B. suis – pigs *犬种-狗 *B. canis – dogs 绵羊副皋种-羊 B. ovis – sheep B. neotoma – desert wood rat 沙林鼠种 -沙漠沙林鼠 *B. pinnepedialis – seals *B. ceta – porpoises, whales • 几个物种感染海洋哺乳动 B. ????? – dolphins 物 B. microti – rodents *B. Inopinata - human *pinnepedialis种 -海豹 *ceta种 -海豚，鲸 ????? 种-海豚 ????? 种 -其他 *表示感染人类 Brucellosis – Introduction • Brucella sp. are thought to • 布鲁氏菌被认为是比较具 be relatively species specific 有物种特异性 • Partly true in that several • 部分是正确因为这几个物 species have multiple hosts 种有多个宿主 • For example, B. suis infects pigs mainly but also man, • 举例来说，布鲁氏菌猪种 cattle, dogs, horses and 主要感染猪，也感染人， sheep 牛，狗，马，羊 • Problem with mixed husbandry and where • 问题与混合畜牧业饲养和 people live in close 那里的人生活在接近农场 proximity to farm animals 动物 • May cause misdiagnosis • 可能会导致误诊 • Can evade the immune • 可以逃避免疫反应 response Brucellosis – Introduction • Brucella sp. are intracellular • 布鲁氏菌是细胞内的寄生 bacteria which reside in 细菌，其中居住在起吞噬 scavenge