海瑟·培根博士-犬糖尿病的诊断和处理·第二届兽医大会专题.pdf

犬糖尿病的诊断和处理 Dr Heather Bacon BSc (Hons) BVSc CertZooMed MRCVS Jeanne Marchig International Centre for Animal Welfare Education 海瑟·培根博士 兽医学学士，英国皇家兽医医学院兽医医学硕士证书 爱丁堡大学Jeanne Marching动物福利教育中心动物福利教育讲师 Blood Glucose血糖 Blood glucose血糖 Normal Blood glucose正常血糖值 2.7 – 7.5mmol/L毫摩尔/升or 50-130mg/dl 毫克/公升 2.2mmol/L 毫摩尔/升(40mg/dl毫克/公升) = Hypoglycaemia – must treat低血糖——需 接受治疗 10-15mmol/L毫摩尔/升(180-270mg/dl毫克/ 公升) Renal threshold肾阈 14mmol/l 毫摩尔/升(250mg/dl毫克/公升) Maximum safe blood glucose level in dogs 犬只最大安全血糖值 16.7mmol/l毫摩尔/升(300mg/dl毫克/公升) Maximum safe blood glucose level in cats 猫类最大安全血糖值 Renal threshold肾阈值 Level at which kidneys will start to excrete glucose into the urine在怎样的情况下肾脏会向尿液中分泌 血糖 10-15mmol/L 毫摩尔/升(180-270mg/dl毫克/公升) Renal threshold肾阈值 Glucose causes increased osmolarity of urine血糖 会增大尿液的渗透压 Results in polyuria causing dehydration and increased thirst会引起多尿症，并由此引发脱水， 口干 Animal becomes polyuric and polydipsic动物会变 得多尿和烦渴 Prevented by the normal action of insulin可以通过 注射胰岛素进行预防 Insulin胰岛素 Hormone produced by the Islet beta cells in the pancreas in response to rising blood glucose levels应对不断上升的血糖值，胰腺会分泌一种激 素，是由胰岛β细胞所产生的一种激素 Role:作用 Decrease glucose production by the liver减少肝脏血糖 的产生 Increase glucose uptake by cells加快细胞吸收血糖 Result = a decrease in circulating blood glucose 结果：减少血流中的血糖含量 Action of insulin 胰岛素的工作原理 INSULIN GLUCOSE 胰岛素 MOLECULES 血糖分子 INSULIN RECEPTOR 胰岛