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ARTICLE IN PRESS
E U R O P E A N J O U R N A L O F C A N C E R x x x ( 2 0 1 0 ) x x x – x x x
a va il ab l e a t w w w . s c i e n c ed i r e c t. c o m
journal homepag e: www.ejc
Frameless single-session robotic radiosurgery of liver
metastases in colorectal cancer patients
S. Stintzing a,*, R.T. Hoffmann b, V. Heinemann a, M. Kufeld c, A. Muacevic c
a Department of Hematology and Oncology, University Hospital Grosshadern, University of Munich, Marchioninistrasse 15,
81377 Munich, Germany
b Institute of Clinical Radiology, University Hospital Grosshadern, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
c European Cyberknife Center Munich, Max-Lebsche-Platz 31, 81377 Munich, Germany
A R T I C L E I N F O A B S T R A C T
Article history: Introduction: Due to advanced chemotherapy regimens, patients presenting with residual
Received 30 July 2009 liver metastases of colorectal cancer (CRC) has increased. Surgery of residual metastases
Received in revised form 23 enhances overall survival, but surgical resection is often limited. Less invasive techniques
December 2009 have been invented to enhance local disease control. We investigated in a selected patient
Accepted 14 January 2010 cohort local control of liver metastasis from CRC using robotic radiosurgery.
Available online xxxx Methods and materials: In this study patients with colorectal liver metastases were prospec-
tively followed after having been treated with single-session radiosurgery using
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