Influence of body mass index and serum lipids on the.pdfVIP

Nutrition, Metabolism Cardiovascular Diseases (2011) 21, S7eS13 availabl e at ww w. s c i en c ed i r e c t .c o m j o u r n al h o m e p a g e : w w w .e l s e vi e r . c o m /l o c at e / n m c d Influence of body mass index and serum lipids on the cholesterol-lowering effects of almonds in free-living individuals a,* ´a,b b b,c K. Jaceldo-Siegl , J. Sabate , M. Batech , G.E. Fraser a Department of Nutrition, School of Public Health, Loma Linda University, 24951 North Circle Drive, Loma Linda, CA 92350, USA b Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, USA c Department of Cardiology, School of Medicine, Loma Linda University, USA Received 12 August 2010; received in revised form 15 March 2011; accepted 15 March 2011 KEYWORDS Abstract Background and aims: Short-term (4e9 weeks) human feeding trials have shown Nuts; nut consumption to reduce serum total cholesterol (TC) and LDL-cholesterol (LDL). We hypoth- Almonds; esized that individual levels of BMI, LDL, TC and triglycerides modify the cholesterol-lowering BMI; effect of almonds in a 24-week almond supplementation trial in a free-living population. Serum lipids; Methods and results: We performed secondary analysis on data from a previously published Free-living; study. Using a sequential study design, all participants followed their habitual diets during Long-term study; the first six months (control), and then consumed an almond-supplemented diet Interaction (habitual þ almonds)