金丝矮的陀陀植物中甾体生物碱的分离与化学结构.pdf

维普资讯 有虮化 YOUJIHUAXUE，3990．10，41～{3 研究通讯 金丝矮陀陀植物中甾体生物碱的分离与化学结构 邱明华、最瑞辩 李 皂荣、用 盟 (中国科学院昆明植物研究所，邑明，6502{)4) Isolation and ChemicalStructuresofSteroidalAlkaloidsfrom Pachy— sandra AxlllarisFRANCH CHIU M ing—Hua， NIE Rui—Lin ，LIZhong-Rong， ZHOU Jun (“nuringIn~ilftat~。，Bot~fiy，Academi口Sinic口，650204Kunmig) Abstract：Thechemicalstructuresofsteroidalalkaloidsisolated from Bachysandra term inalis have been studied by Professor Kikuchi at Kyoto University， these alkaloids were galled Pachysandra alkaloids． ’。Recently． we havestudied the steroidalalka]ojds from pachysandra 酣 illaris collected jn Yunnan ofCHINA ． 。 ． By iTleansof system atic isolation。22 steroida1alkaloids werejsolated in crystalline f0rm from the 95 EtO}Iextractsof P axiltaris．Thebasiccharacteristicsof these compoundsare ． listed in Tab l The】r chem ical structureswereelucidated based on IR ． UV． NM R S． spectra andchemica1evideces and are shown in Tab 1．AlJthecompoundsbelongt6 steroidal alkaloidsofpregnanetype．i ofwhich．i．e．iso—spiropachi／sine (2)，spiropachys!~eB (3 ， pachyadimine^，B (1T，18)，axillarineA-F (21，2口，13，14 1O，15)，pachysamine：H． G(5，7》，pachysanaximineA (12)，axillaridineA (16)，pachyaxiosideA，B (¨，l9)and epi—pachysamine B (8)，are naturalproducts reported for the firsttime． The detail of the ． isolatioriand characterization ofthesenew compoundssba】lbereported elsewhere． Descriptor： steroidalalkaloid，naturalproducts，chem icalstructure ’ 、 最近，我们研究了云南 的。金丝矮陀陀植 化台物 中，异螺旋富