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* * * * * * * * * * Once a pathogen produces infection, antimicrobial treatment may be essential. However, antimicrobial use promotes selection of antimicrobial-resistant strains of pathogens. As the prevalence of resistant strains increases in a population, subsequent infections are increasingly likely to be caused by these resistant strains. Fortunately, this cycle of emerging antimicrobial resistance / multi-drug resistance can be interrupted. Preventing infections in the first place will certainly reduce the need for antimicrobial exposure and the emergence and selection of resistant strains. Effective diagnosis and treatment will benefit the patient and decrease the opportunity for development and selection of resistant microbes; this requires rapid accurate diagnosis, identification of the causative pathogen, and determination of its antimicrobial susceptibility. Optimizing antimicrobial use is another key strategy; optimal use will ensure proper patient care and at the same time avoid overuse of broad-spectrum antimicrobials and unnecessary treatment. Finally, preventing transmission of resistant organisms from one person to another is critical to successful prevention efforts. * These 12 steps to Prevent Antimicrobial Resistance among hospitalized adults are action steps that clinicians can and should take now. They are designed to optimize patient safety and the outcome of infectious disease management. Together, these steps can prevent the emergence and spread of antimicrobial-resistant pathogens. * These 12 steps to Prevent Antimicrobial Resistance among hospitalized adults are action steps that clinicians can and should take now. They are designed to optimize patient safety and the outcome of infectious disease management. Together, these steps can prevent the emergence and spread of antimicrobial-resistant pathogens. * Infectious diseases specialists are one important resource for providing input, but many other professionals also contribute to
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