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中大生物化学试题答案与评分标准(2005秋季,A卷)
生物化学I(2005年秋季学期, A卷)
专业(班级): 姓名: 学号:
阅卷教师:
题号 一 二 三 四 五 合计 分数 《中山大学授予学士学位工作细则》第六条:“考试作弊不授予学士学位”。
1. With regard to amino acids, which statement is false?
A) Amino acids can act as proton donors and acceptors.
B) All amino acids discovered in organism are L enantiomers.
C) An L amino acid can be Dextrorotary.
D) Non-standard amino acids can be found in the hydrolysis product of a protein.
2. In a highly acidic solution, pH = 1.3, the dominant form of glycine is:
A) NH2-CH2-COOH;B) NH3+-CH2-COOH;C) NH2-CH2-CO–;D) NH3+-CH2-COO–.
3. In the isoelectric form of a tetrapeptide:
A) The amino and carboxyl termini are not charged.
B) Two internal amino acids of the tetrapeptide cannot have ionizable R groups.
C) The total net charge is zero.
D) Only the amino and carboxyl termini contribute charge.
4. Which would elute first from a gel-exclusion chromatographic column?
A) a negatively charged protein of MW=40,000
B) a positively charged protein of MW=40,000
C) a protein at its isoelectric point of MW=30,000
D) a polysaccharide of MW=100,000
5. In an aqueous solution, protein conformation is determined by two major factors. One is the formation of the maximum number of hydrogen bonds. The other is the:
A) formation of the maximum number of hydrophilic interactions.
B) maximization of ionic interactions.
C) minimization of entropy by forming a water solvent shell around the protein.
D) placement of all hydrophobic amino acid residues within the interior of the protein.
6. You can destabilize a duplex DNA molecule in an aqueous solution by
A) Decreasing the concentration of salt.
B) Decreasing the concentration of organic solvents.
C) Adjusting the pH to a value near 7.
D) Adding a detergent.
7. With regard to DNA, which statement is false?
A) Triple helix and tetraplex tend to appear at sites where replication, recombination or transcription is initiated or regulate
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