hiv阳性孕产妇所生婴儿生长发育状况评价.doc

﹒论著﹒ HIV阳性孕产妇所生婴儿生长发育状况评价 朱岚,计国平1,2,吴跃飞3,卫平4，李松1，胡迅嘉1 （1.安徽医科大学公共卫生学院流行病与卫生统计学系，安徽 合肥 230032；2.安徽省妇幼保健所，安徽 合肥 230061；3.安徽省宣城市妇幼保健所，安徽 宣城 242000；4.安徽省泾县妇幼保健所，安徽 泾县 242500） 摘要：目的 了解安徽省艾滋病病毒（HIV）阳性孕产妇所生婴儿在出生及12月龄内的生长发育状况。方法 采用回顾性队列研究方法，以安徽省HIV阳性孕产妇所生新生儿队列为暴露组，以安徽省宣城市泾县一般孕产妇所生新生儿队列为非暴露组，按照1︰2比例匹配，比较两组婴儿在出生及1、3、6、9、12月龄的生长发育状况。同时将所得的两组儿童的生长发育数据与世界卫生组织（WHO）标准进行比较。 结果 暴露组共有新生儿、1、3、6、9和12月龄各189、120、112、98、93和93人。暴露组儿童与WHO标准比较结果显示仅男童出生体重和出生身长低于WHO标准（P＜0.05）,其他月龄男童和各月龄女童生长发育情况良好。非暴露组与WHO标准比较结果显示各月龄儿童身长和体重均优于WHO标准。暴露组与非暴露组婴儿的身长、体重差异集中在6月龄及以前，但两组在各月龄的肥胖、超重、消瘦检出率差异均无统计学意义。 结论 HIV阳性孕产妇所生婴儿的体重和身长发育良好；在6月龄前的身长和体重略低于同月龄一般儿童，随后则与一般儿童趋于一致；超重和肥胖比例较高，应引起重视。 关键词：艾滋病病毒阳性孕产妇；婴儿;生长发育 中图分类号：R 373.9 文献标志码：A 文章编号：1672-5662（2015）11-0000-00 Assessment of growth and development of infants born to HIV-positive mothers ZHU Lan, JI Guo-ping ,WU-Yue-fei, et al. （Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University. Hefei, 230032, China） Abstract：Objective To identify the growth status of infants born to HIV-positive mother. Method This is a historical cohort study. The newborn cohort born to HIV-positive mothers in Anhui province were selected as exposed group, and the newborn cohort born to HIV-negative mother from Jingxian county in Anhui were matched 2:1 as unexposed group. The growth indicators of exposed and unexposed groups were compared with WHO standard and with each other. Result There were 189 newborns, 120 1-month-old infants, 112 3-month-old, 98 6-month-old, 93 9-month-old and 93 12-month-old infants in the exposed group. Compared with WHO standards, the mean length and weight at all age in the exposed group were better, except for the boys’ mean birth length, and all the indicators were better in the unexposed group. Compared with the unexposed group, the mean length and weight were smaller at 6-month-old and younger age, and similar at 9-month-old and older age in the exposed group. There were no statistical