生物矿化与仿生材料Biomim06_Class.ppt

Classification: Biomimetic and Biologically Inspired Materials Synthesis Last lecture: eggshell biomineralization collagen, formation of bone Today: Classification: biomimetic and biologically inspired materials synthesis Outlook to following lectures Literature: S.Mann (Ed.) “Biomimetic materials chemistry” (VCH, Weinheim 1996) S.Mann “Biomineralization and biomimetic ma-terials chemistry” J.Mat.Chem. 5 (1995) 935. M.Fritz, A.Belcher, M.Radmacher, D.Walters, P.Hansma, G.Stucky, D.Morse, S.Mann ?Flat pearls from biofabrication of organized compo-sites on inorganic substrates“ Nature (1994) 371 49. N.Pellerin, J.Staley, T.Ren, G.Graff, D.Treadwell, I.Aksay “Acidic biopolymers as dispersants for ceramic processing” Mat.Res.Soc.Symp.Proc. (1991) 218 123. Overview Application of Living Organisms ?Flat Pearls“ Haliotis rufescens ?red abalone“ as ?host“ for glass substrates mineralization within 14 days academic approach utilization of all stages of construction Application of Living Organisms in-situ biosynthesis of dispersants cultivation of azotobacter vine-landii in Al2O3-suspensions biopolymer secreted by bacteria stabilizes dispersion ? control of precipitation(? surface specificity) Application of “Biogenic” Materials Ferritin Mineralization of “unbiological” materials (e.g. CdS) in Ferritin core supramol. preorganization (surface recognition) vectorial regulation Application of Biogenic Materials Mineralization in collagen collagen as matrix for double diffusion experiments mineralization in gel supramol. preorganization surface recognition Application of Biogenic Materials Crystallization in presence of soluble mollusk proteins extraction of proteins from extracellular matrix mineralization experiments in vitro surface recognition vectorial regulation Biomimetic Synthesis Langmuir-films mineralization on monolayer of amphiphilic at gas/liquid interface SAMs self-assembled monolayers of C14-18-silanes on Si single crystals surface recognition vec