25-初诊不孕不夫妇中男性精液质量分析.doc

　　　初诊不孕不育夫妇中男性精液质量分析 高玉芳1,2 赵联营1 李 睿2 冯美宁2 徐 静2 1. 陕西省咸阳市中心医院检验科（陕西 咸阳 712000） 2. 陕西省咸阳市中心医院生殖医学科，陕西省辅助生殖中心咸阳分中心， 　　摘要 目的 初步了解来我院初诊的不孕不育夫妇中男性精液质量现况。方法 收集2009年8月至2010年11月来我院生殖医学科初诊的1108对不孕不育夫妇中男性精液常规检查结果，对精液参数进行统计分析，并以年龄分组，分析并比较各组精液参数。结果 精液常规检查结果中，精液参数均正常占28.6%（317/1108），无精子症占3.5%（39/1108），至少有一项精液参数异常占67.9%（752/1108）。异常精液参数主要以精子活力异常（85.6%，644/752）为主，精子密度异常（35.9%,270/752）次之。各年龄组间仅精子活力和活率有统计学差异（p＜0.05），且随年龄的增加有下降趋势。结论：不孕不育夫妇中男性精液质量异常占较大比例，精子活力异常是导致生育力低下的主要原因。及早就诊对不孕不育夫妇非常关键。 关键词 不孕不育；精液质量；精子密度 中图分类号R446. 9 文献标识码 B Semen quality of men in preliminary diagnostic infertile couples Gao Yufang1,2, Zhao Lianying1, Li Rui2, Feng Meining2, Xu Jing2 1. Department of Laboratory Diagnosis,Central Hospital of Xianyang, Shanxi Xianyang, 712000, China 2. Reproductive Center, Central Hospital of Xianyang,Shanxi Xianyang 712000,China) Abstract Objective To investigate the semen quality of men in preliminary diagnostic infertile couples. Methods: 1108 cases of semen routine examination results from men in preliminary diagnostic infertile couples were collected between August 2009 to November 2010,semen parameters were analyzed statistically.They were divided into 5 groups according to age, semen parameters in each group were analyzed and compared. Results Of semen routine examination results, 28.6%（317/1108）had all normal semen parameters, 3.5%（39/1108）azoospermatism,and 67.9%（752/1108）had at least one of the semen parameters below normal threshold value. Of abnormal semen parameters , (85.6%,644/752)had sperm rapid progressive motility（a%）or sperm progressive motility[ (a+b)%] below normal threshold value,and （35.9%,270/752）had sperm concentration below normal.Only sperm rapid progressive motility（a%）,sperm progressive motility[ (a+b)%] and total motility[(a+b+c)%] had statistical difference（p0.05）among the different age groups and these three semen parameters had a descend tendency with the increase of age.Conclusion：A high proportion of i