Oddi括约肌运动功障碍的诊断和治疗.doc

Oddi括约肌运动功能障碍的诊断和治疗司丽娟, 任建林, 董菁, 厦门大学附属中山医院消化内科, 厦门大学消化疾病研究所 福建省厦门市 361004 任旭, 黑龙江省消化病医院 黑龙江省哈尔滨市 150001 迟宝荣, 吉林大学第一医院消化内科 吉林省长春市 130021 作者贡献分布: 此课题由司丽娟、任旭教授设计并完成操作; 由司丽娟、董菁、任建林教授撰写; 迟宝荣教授修改审核. 通讯作者: 迟宝荣, 130021, 吉林省长春市, 长春市新民大街1号, 吉林大学第一医院消化内科. baorong_chi@ 电话: 0431-5612437 收稿日期: 2007-08-27 修回日期: 2007-12-06 Diagnosis and treatment of Oddi sphincter dyskinesia Li-Juan Si, Jian-Lin Ren, Jing Dong, Xu Ren, Bao-Rong Chi Li-Juan Si, Jian-Lin Ren, Jing Dong, Department of Gastroenterology, Zhongshan Hospital of Xiamen University, Gastroenterology Institute of Xiamen University, Xiamen 361004, Fujian Province, China Xu Ren, Digestive Disease Hospital of Heilongjiang Province, Harbin 150001, Heilongjiang Province, China Bao-Rong Chi, Department of Gastroenterology, the First Hospital of Jilin University, Changchun 130021, Jilin Pro-vince, China Correspondence to: Bao-Rong Chi, Department of Gastroenterology, the First Hospital of Jilin University, 1 Xinmin Street, Changchun 130021, Jilin Province, China. baorong_chi@ Received: 2007-08-27 Revised: 2007-12-06 Abstract Oddi sphincter dyskinesia is a digestive disease which is difficult to diagnose in time and treat properly. Although some methods can be used to diagnose Oddi sphincter dyskinesia, no convenient method with a high sensitivity is available at present. Oddi sphincter manometry is considered a golden diagnostic standard for Oddi sphincter dyskinesia. However, it has not been widely used in clinical practice, because it is inaccurate and unfaithful and often leads to severe complications. Only few patients with Oddi sphincter dyskinesia could be treated with chemical drugs. At present, endoscopic sphincterotomy (EST) is the best choice of treatment for Oddi sphincter dyskinesia. This paper discusses the role of Oddi sphincter manometry and EST in treatment of Oddi sphincter dyskinesia. Some patients need to undergo transduodenal sphicteroplasty or anastomosis of bile duct with intestine. Key Words: Oddi sphincter