穿琥宁注射液治疗病毒性肺炎的临床观察.docVIP

穿琥宁注射液治疗病毒性肺炎的临床观察 　　doi：10.3969/j.issn.1007-614x.2014.12.59 　　摘 要 目的：探索穿琥宁注射液治疗病毒性肺炎的临床疗效。方法：收治病毒性肺炎患者160名，随机分成对照组和观察组。对照组服用普通抗病毒药物金刚烷胺治疗，观察组注射穿琥宁注射液进行治疗，两组均以7天为1疗程。结果：观察组经治疗后总有效率90.00%，明显高于对照组（63.75%），两组比较差异有统计学意义（P0.05）。观察组头痛、发热、咽痛等症状消失的时间明显短于对照组相同症状消失的时间，两组比较差异有统计学意义（P0.05）。结论：穿琥宁注射液对于治疗病毒性肺炎有较好疗效，值得在临床推广。 　　关键词 穿琥宁注射液 病毒性肺炎 临床疗效 　　Clinical observation of potassium dehydroandrograpolide succinate injection in the treatment of viral pneumonia 　　Xu Hui，Chen Fenggan 　　Medical Department，Dongtan Coal Mine Hospital of Zoucheng City，Shandong 273512 　　Abstract Objective：To explore the clinical efficiency of potassium dehydroandrograpolide succinate injection in the treatment of viral pneumonia.Methods：160 patients with viral pneumonia were selected.They were randomly divided into the control group and the observation group.The control group were treated with common antiviral drugs amantadine.The observation group were treated with potassium dehydroandrograpolide succinate injection.The course of treatment of both groups was 7 days.Results：After treatment，the total effective rate of the observation group was 90.00%.It was significantly higher than 63.75% of the control group.The difference was statistically significant（P0.05）.The headache，fever，sore throat and other symptoms disappear time of the observation group were significantly shorter than these of the control group.The difference was statistically significant（P0.05）.Conclusion：Potassium dehydroandrograpolide succinate injection in the treatment of viral pneumonia has a good effect.It is worthy of promotion. 　　Key words Potassium dehydroandrograpolide succinate injection；Viral pneumonia；Clinical efficacy 　　最近有研究表明，中药材穿心莲内酯具有抗炎活性，可以灭活流感病毒及呼吸道病毒[1，2]。穿琥宁注射液是由穿心莲内酯提炼而来，本研究观察了穿琥宁注射液治疗病毒性肺炎的临床疗效，报告如下。 　　资料与方法 　　选取160例患者，男80例，女80例，年龄16～33岁。随机分为两组，观察组80例，男女各40例；对照组80例，男女各40例。两组患者均有上呼吸道感染、头痛和发热等病毒性肺炎症状，并排除其他病毒性感染的可能。且两组患者的性别、年龄差异无统计学意义（P0.05），具有可比性。 　　治疗方法：观察组注射穿琥宁注射液，60～80mg/次，2次/日。每2小时量1次体温，并观察患者是否有头痛、乏力