奥美拉唑联合云南白药治疗胃溃疡出血的疗效研究.docVIP

奥美拉唑联合云南白药治疗胃溃疡出血的疗效研究 　　【摘 要】目的：观察奥美拉唑联合云南白药治疗胃溃疡出血的临床疗效。方法：收集伊宁市人民医院自2006年6月至2010年6月经胃镜病理证实为胃溃疡出血122例患者，随机分为治疗组和对照组，分别为64例和58例。治疗组采用奥美拉唑40mg，静点，一日两次；云南白药1g，口服，一日三次；对照组采用单药奥美拉唑，用法同治疗组，疗程均为两周。比较两组的治疗效果及不良反应。结果：治疗组和对照组止血总有效率分别为98.4%和74.0%，差异有统计学意义（P0.05）。两组均无严重不良反应。结论：奥美拉唑联合云南白药治疗胃溃疡出血效果显著，安全、可靠。 　　【关键词】奥美拉唑；云南白药；胃溃疡；出血 　　【中图分类号】R573 【文献标识码】A 【文章编号】1004-7484（2013）05-0204-01 　　The Curative Effect Study of Omeprazole Combined with YUN NAN BAI YAO in Treating Gastric Ulcer Hemorrhagic 　　Zhang Wenxiao， Tang Xiaojun， Liu Qi， et al. Emergency Department and Internal Medicine， People’s Hospital of Yining 835000； Emergency Department， The Fourth Agriculture Hospital of Xinjiang 835000；Department of Gastrointestinal Surgery， Tumor hospital of Xinjiang Medical University 830011 　　【Abstract】Objective：To observe clinical curative effect of Omeprazole combined with YUN NAN BAI YAO in treating gastric ulcer hemorrhagic. Methods：122 cases confirmed gastric ulcer hemorrhagic by gastric ulcer hemorrhagic and pathology in Yining people’ Hospital were collected from June 2006 to June 2010， and were divided into two groups， Experimental Group （EG） and Control Group （CG）. The number of EG and CG was 64 and 58. EG were treated with Omeprazole （40mg， ivgtt， bid） and YUN NAN BAI YAO （1g， po， tid）， meanwhile CG were treated with only Omeprazole （40mg， ivgtt， bid）. After two weeks， curative effect and adverse reaction of these two groups were recorded and compared. Results：The total effective rate of two groups was 98.4 percent and 74.0 percent separately （P0.05）. there were no severe adverse reaction in two groups. Conclusion：It is very significant to treat gastric ulcer hemorrhagic by Omeprazole combined with YUN NAN BAI YAO， and also safe and reliable. 　　【Key words】Omeprazole； YUN NAN BAI YAO；gastric ulcer；hemorrhage 　　胃溃疡出血是较常见的内科急症[1]，药物治疗仍是目前采用的首选方法，而安全、有效的药物治疗是减少溃疡出血手术率和病死率的主要措施。将收集自2006年6月至2010年6月伊宁市人民医院胃镜病理证实为胃溃疡出血的患者122例，将经奥美拉唑联合云南白药治疗的64例患者与单纯使用奥美拉唑治疗的58例患者，从临床疗效及安全方面进行