《病理考试Cardiac.ppt

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2016-12-29 发布于北京
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《病理考试Cardiac.ppt

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为什么肥大心肌最终转为衰竭？ Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. (Mechanisms of heart failure) 第五节心力衰竭的发病机制 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 心肌正常舒缩所需要的基本物质：（一）收缩蛋白 ①肌球蛋白（粗肌丝） ②肌动蛋白（细肌丝） Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. （二）调节蛋白 ①向肌球蛋白 ②肌钙蛋白（三）钙离子（四）ATP Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 一、心肌收缩力降低 (Decreased myocardial contractility) Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. (一) 心肌收缩蛋白的破坏 (Injuries of myocardial contractile protein) Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 心肌细胞坏死（myocyte necrosis）心肌细胞凋亡（myocyte apoptosis） Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. (二)心肌能量代谢紊乱心肌能量生成障碍 (impaired energy production) 心肌储能减少 (reduced energy reserve) 能量利用障碍 (impaired energy utilization) (Disorder of myocardial energy metabolism) Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 1.心肌能量生成障碍 (impaired energy production) 最常见的原因: 心肌缺血缺氧 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 2.心肌储能减少 (reduced energy reserve) 磷酸肌酸激酶 ATP 肌酸磷酸肌酸(CP) 心肌肥大时，磷酸肌酸激酶活性↓，储能的CP ↓ Evaluation only. Created with A