Rapid Information on OLM No 205 140106Rapid Information on OLM No 205 140106.doc

Rapid Information on OLM No 205 140106Rapid Information on OLM No 205 140106.doc

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Rapid Information on OLM No 205 140106Rapid Information on OLM No 205 140106

Rapid Information on Olmesartan and other ARBs No.205 2014/01/06                            Be the first to know!          (Toru Komai, Ph.D.) 205-1:Treatment with olmesartan effectively attenuated cognitive impairment and BBB disruption as well as renal injury in salt-treated type 2 diabetic mice. Co-administration of suppressive dose of the CCB, azelnidipine significantly exaggerated the protective effects of olmesartan. 2-3 Title:Calcium Channel Blocker Enhances Beneficial Effects of an Angiotensin II AT1 Receptor Blocker against Cerebrovascular-Renal Injury in type 2 Diabetic Mice. 205-2: Extensive clinical evidence has demonstrated the excellent efficacy and tolerability profile of olmesartan including in elderly patients. (Review)   4 Title:Olmesartan in the treatment of hypertension in elderly patients: a review of the primary evidence. 205-3: Olmesartan, captopril, melatonin and C21 exerted a similar level of renoprotective effects in doxorubicin-induced nephrotoxicity in rats.    5-6 Title:Protective effect of captopril, olmesartan, melatonin and compound 21 on doxorubicin-induced nephrotoxicity in rats. 205-4:The combination of rosuvastatin with telmisartan increased the possibly antiatherosclerotic HDL-Lp-PLA2 activity, but not with olmesartan.     6 Title:Combining Rosuvastatin With Angiotensin-Receptor Blockers of Different PPARγ-Activating Capacity: Effects on High-Density Lipoprotein Subfractions and Associated Enzymes. Abbreviations: BP: blood pressure, SBP/DBP: systolic/ diastolic BP, RAS: renin–angiotensin system, Ang II: angiotensin II, ARB: angiotensin II receptor blocker, CCB: calcium channel blocker, CKD: chronic kidney disease, T2DM: type 2 diabetes mellitus, HR: hazard ratio, OR: odds ratio, 205-1:Treatment with olmesartan effectively attenuated cognitive impairment and BBB disruption as wel

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