[概述、合成抗菌药.ppt

Review 1、常见病原体种类 2、G+菌与G-菌的细胞壁结构 Tab. Fig. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 化疗药物 Chemotherapeutic Drugs 第30章 概述 Introduction 第35章 人工合成抗菌药物 Artificial synthetic antibacterial drugs The department of pharmacology: 辛志伟 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. To be master： 基本概念；喹诺酮类和磺胺类药物的药理作用、临床应用和不良反应。 To be familial with：抗菌药物的抗菌作用机制；病原体的耐药性。 To be known：甲氧苄啶和硝基呋喃类药物的药理作用、临床应用和不良反应。 Professional terms：antibiotics；antibacterial spectrum；minimum inihibitory concentration, MIC；minimum bactericidal concentration, MBC； post-antibiotic effect，PAE 目的和要求 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 第30章 抗菌药物概述 Introduction for antimicrobial drugs 一、基本概念 1、化疗药物（chemotherapeutic drugs）：指抗微生物药、抗寄生虫药和抗肿瘤药的合称。 2、化疗（化学治疗，chemotherapy）：用化疗药物治疗感染性疾病或肿瘤性疾病的方法。 3、抗菌谱（antibacterial spectrum）：抗菌药的抗菌作用范围。 Fig. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 化疗1 5 Introduction 2 4、抗菌活性（antibacterial activity）：指抗菌药物抑制或杀灭病原菌的能力。常用最低抑菌浓度（minimum inihibitory concentration, MIC）和最低杀菌浓度（minimum bactericidal concentration, MBC）来表示。 5、抗药性（耐药性，resistance）：专指病原体或肿瘤细胞对化疗药的不敏感性。 6、化疗指数（chemotherapeutic index, CI）：化疗药的治疗指数（化疗药物的：LD50/ED50）。 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 20