生物信息学试题..docx

泰山学堂生命取向2013-2014学年春季学期《生物信息学》期末考试题课程名：《生物信息学》班级：泰山学堂生命取向2010级、2011级考试时长：2小时考试时间：2014年5月15日14：00-16：00考试地点：知新楼D座3层机房考试方式：机试、开卷试卷份数：0份，机试无需印刷题号1234567总分满分分数15151515151515105100得分姓名学号第1题（15分）在Genbank中寻找gene locus为MA4546的核酸，并：指出其编码的蛋白质是什么（4分）（2）指出其所在核酸的accession number（2分）及在这段核酸上的位置（起始碱基和终止碱基的位置）（2分）（3）计算该基因编码蛋白的分子量及等电点（2分）（4）查找一篇有关该蛋白的论文，指出论文的作者、题目、发表年份、杂志、页码（5分）（1）此蛋白质为甲基辅酶M还原酶（2）accession number为：NC_003552 起始碱基为5596675 终止碱基为5598387)（3）共570氨基酸预测的等电点为5.14，相对分子质量为62075.21 道尔顿（4）题目：The genome of M. acetivorans reveals extensive metabolic and physiological diversity作者：/pubmed?term=Galagan%20JE%5BAuthor%5Dcauthor=truecauthor_uidalagan JE1,?/pubmed?term=Nusbaum%20C%5BAuthor%5Dcauthor=truecauthor_uidusbaum C,?/pubmed?term=Roy%20A%5BAuthor%5Dcauthor=truecauthor_uidoy A,?/pubmed?term=Endrizzi%20MG%5BAuthor%5Dcauthor=truecauthor_uidndrizzi MG,?/pubmed?term=Macdonald%20P%5BAuthor%5Dcauthor=truecauthor_uidacdonald P,?/pubmed?term=FitzHugh%20W%5BAuthor%5Dcauthor=truecauthor_uiditzHugh W,?/pubmed?term=Calvo%20S%5BAuthor%5Dcauthor=truecauthor_uidalvo S,?/pubmed?term=Engels%20R%5BAuthor%5Dcauthor=truecauthor_uidngels R,?/pubmed?term=Smirnov%20S%5BAuthor%5Dcauthor=truecauthor_uidmirnov S,?/pubmed?term=Atnoor%20D%5BAuthor%5Dcauthor=truecauthor_uidtnoor D,?/pubmed?term=Brown%20A%5BAuthor%5Dcauthor=truecauthor_uidrown A,?/pubmed?term=Allen%20N%5BAuthor%5Dcauthor=truecauthor_uidllen N,?/pubmed?term=Naylor%20J%5BAuthor%5Dcauthor=truecauthor_uidaylor J,?/pubmed?term=Stange-Thomann%20N%5BAuthor%5Dcauthor=truecauthor_uidtange-Thomann N,?/pubmed?term=DeArellano%20K%5BAuthor%5Dcauthor=truecauthor_uideArellano K,?/pubmed?term=Johnson%20R%5BAuthor%5Dcauthor=truecauthor_uidohnson R,?/pubmed?term=Linton%20L%5BAuthor%5Dcauthor=truecauthor_uidinton L,?/pubmed?term=McEwan%20P%5BAuthor%5Dcauthor=truecauthor_uidcEwan P,?/pubm