cardiac arrest Brain Injury from Cardiac Arrest in Children.doc

cardiac arrest Brain Injury from Cardiac Arrest in Children 导读：就爱阅读网友为您分享以下“Brain Injury from Cardiac Arrest in Children”的资讯，希望对您有所帮助，感谢您对92的支持! BRAININJURYINCHILDREN151 Theimpactofglobalbrainischemiaonfunctionaloutcomeduringde-velopmentallysensitive拻eperiodsofskillacquisitionandtheroleofplasticityinrecoveryfromglobalischemiahasnotbeensystematicallystudied.Onechallengeisthatinjuryobtainedinyoungpatientsmaynotbecomeapparentuntilthefunctionalcorrelatesarerequiredfornormalbehaviorandaretest-able.Forexample,childrenwhohavelearningdisabilitiesareoftennotdi-agnoseduntiltherequisitelearningskillsbecomenecessaryforschoolperformance.Agreaterunderstandingofthedynamicbetweeninjuryanddevelopmenthasconsiderablepotentialbene?tforchildrenwhohaveische-micbraininjury. Clinicalexperience YoungandSeidel[27]recentlysummarizedtheresultsfrom44studiesre-portingon3094pediatricpatientswithcardiopulmonaryarrest.Thedatashowedanoverallsurvivalratefromcardiopulmonaryarrestof13%,within-hospitalarrestratesbeinghigherthanout-of-hospitalarrestrates(24%versus9%).Mostofthereviewedstudiesreportedgoodneurologicoutcomeinapproximately60%ofsurvivors;however,comparisonbetweenstudiesisdi?cultbecauseofthedi?erencesininclusioncriteriaandthedef-initionof憫egood拻oneurologicoutcome.Neurologicoutcomeassessmentsthattargetmotorfunctionandrudimentarylife-skilltaskssuggestthatmostpatientshavefullrecoveryorseveredisability[28–35].Patientswhohavepooroutcomehavegenerallysu?eredasevere,acuteasphyxialevent.Amongchildrenwithgoodneurologicoutcome,assessmentsthatmeasureIQorpsychocognitivefunctionoftenrevealimpairedperformance[36–40].Robertsonandcolleagues[39]recentlypublisheddataonacohortof53childrenyoungerthanage3yearsadmittedtoanICUwhohadtraumaticbraininjury(n?26)orhypoxicischemic(HI)braininjury(n?27)andaninitialGlasgowComaScal