欧洲药典EP8.0 硫酸灰.doc

欧洲药典EP8.0 硫酸灰 导读：就爱阅读网友为您分享以下“欧洲药典EP8.0 硫酸灰”的资讯，希望对您有所帮助，感谢您对92的支持! 2.4.14. SULFATED ASH 硫酸灰分 Ignite a suitable crucible (for example, silica, platinum, porcelain or quartz) at 600+/-50℃ for 30 min, allow to cool in a desiccator over silica gel or other suitable desiccant and weigh. Place the prescribed amount of the substance to be examined in the crucible and weigh. Moisten the substance to be examined with a small amount of sulfuric acid R (usually 1 mL) and heat gently at as low a temperature as practicable until the sample is thoroughly charred. After cooling, moisten the residue with a small amount of sulfuric acid R (usually 1 mL), heat gently until white fumes are no longer evolved and ignite at 600+/-50℃ until the residue is completely incinerated. Ensure that flames are not produced at any time during the procedure. Allow the crucible to cool in a desiccator over silica gel or other suitable desiccant, weigh it again and calculate the percentage of residue. 将合适的坩埚（例如硅、铂、瓷或石英）在600+/-50℃灼烧30分钟，在有硅胶或其它合适的干燥剂的干燥器内冷却，称重。取适当数量样品于上述坩埚内，称重。用适量硫酸（一般1ml）润湿样品，低温缓慢加热直至样品完全灰化，冷却，用少量硫酸（一般1ml）润湿残渣，缓慢加热直至不再生成白烟，在600+/-50下灼烧直到残渣完全烧尽。整个操作中应保证不产生明火。在有硅胶或其它合适的干燥剂的干燥器中冷却坩埚，称重，计算残渣百分比。 If the amount of the residue so obtained exceeds the prescribed limit, repeat the moistening with sulfuric acid R and ignition, as previously, for 30 min periods until 2 consecutive weighings do not differ by more than 0.5 mg or until the percentage of residue complies with the prescribed limit. 如果上述操作所得结果超过要求的限度，则重复用硫酸润湿灰分，高温灼烧30分钟，直到两次称重差异不超过0.5