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《c1cc11943e

Carbon nanodots as peroxidase mimetics and their applications to glucose detection3,3,5,5-四甲基联苯胺(C16H20N2)分子量:240.34 一种新型安全的色原试剂;Carbon nanodots (C-Dots) were found to possess intrinsic peroxidase(过氧物酶)-like activity, and could catalytically(催化地) oxidize 3,3,5,5-tetramethylbenzidine (TMB) by H2O2 to produce a colour reaction. This o?ers a simple, sensitive and selective colorimetric(比色的) method for glucose determination in serum(血液)。(碳纳米点被发现拥有类似过氧物酶的活性,可以催化过氧化氢氧化TMB)C-Dots were first reported in 2004,and have subsequently(随后)attracted considerable(相当的) attention due to their promising advantages.2(碳点04年被发现,由于其优秀的优点随后吸引了大量的关注)C-Dots exhibit several promising advantages compared with quantum dots, such as tunable(可调的)luminescence emission, high stability against photobleaching and blinking.3In addition, C-Dots are biocompatible, small, and have low molecular weight and toxicity, which makes them superior(优秀) to quantum dots.3,4(C-Dots展示几种有前景的优势与量子点相比,如可调发光放射,对于光漂白和闪烁的高稳定性。此外,C-Dots生物适应性,分子小,低分子量和毒性,这使得它们优于量子点)Applications of C-Dots in bioimaging based on their optical(光学的)characteristics have been successfully demonstrated by several groups.4Sun and co-workers demonstrated the potential of passivated C-Dots for two-photon fluorescence imaging of cells,5and used C-Dots for in vivo studies of optical imaging.6Ray et al. applied C-Dots to cellular bioimaging and demonstrated their ability to penetrate into cells.(基于他们的光学特性的应用已经被几个团队成功展示。孙和同事证明了钝化的C-Dots在细胞的双光子荧光成像技术的潜力,并且C-Dots用于体内光学成像的研究。雷等人应用C-Dots于细胞生物成像和证明他们渗透进入细胞的能力)3These applications are important and attractive. Up to now, the activity of the C-Dots as enzymatic mimetics(酶的模拟) has not been reported although there are some works on intrinsic(固有的)peroxidase(过氧物酶)-like activities of other nanoparticles (NPs).7Herein, we demonstrate the intrinsic catalytic activity of C-Dots in the catalysis of oxidation of a peroxidase substrate TMB in the presence of H2O2 to produce a blue color. C-Dots were used successfully for h

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