選择性激光小梁成形术治疗原发性开角型青光眼的一年疗效观察.docVIP

眼科 2007年第16卷第I期 Ophthalmol CHN, 2007,Vol 16, No. 1 37 ·论著· 选择性激光小梁成形术治疗原发性开角型 青光眼的一年疗效观察 王涛 王宁利 【摘要】 目的 研究选择性激光小梁成形术原发性开角性青光眼患者原发性开角性青光眼患者患者于下方180度房角行激光治疗，50点，每个脉冲的能量范围0.~1.4mJ。结果 在患者中有.5%的患者眼压术前的平均眼压为24.3±3.7）mmHg, 手术后的平均眼压为19.1±3.9）mmHg，眼压的下降具有非常显著性差异（P0.001）结论 治疗早期原发性开角性青光眼是安全而有效的。选择性激光小梁成形术follow-up of selective laser trabeculoplasty in primary open-angle glaucoma. Wang Tao, Wang Ning-li. Beijing Tongren Eye Center, Capital University of Medical Sciences, Beijing 100730, China. Corresponding author: Wang Tao, Email: stwang66@ 【Abstract】 Objective To investigate the safety and efficacy of selective laser trabeculoplasty (SLT) in primary open-angle glaucoma (POAG). Design Retrospective case report Participants 47 cases (62 eyes) POAG patients Methods 62 eyes of 47 patients with primary open-angle glaucoma were treated with frequency doubled ND:YAG laser SLT (Selecta Duet). A total of approximately 50 non-overlapping spots were placed over 180 degrees of the trabecular meshwork at energy levels ranging from 0.5 to 1.4 mJ per pulse. After surgery, patients were maintained with the drug regimen identical to that before treatment. The average follow-up was 12 months. Main Outcome Measures Intraocular Pressure (IOP) and Complications. Results After 1 year the average reduction in intraocular pressure (IOP) from the baseline was 5.2 mmHg. The IOP of 72.5% eyes were controlled well. The slight inflammation of anterior chamber occurred in all the cases 1 hour later after SLT and disappered 3 days later automatically. Conclusions SLT is an effective and safe method to lower IOP in primary open-angle glaucoma in the one year follow up. 【Key words】selective laser trabeculoplasty; open-angle Glaucoma/laser treatment 原发性开角型青光眼（primary open-angle glaucoma, POAG）的治疗一直是青光眼领域的一个棘手问题。特别是对于早期POAG而言，药物治疗一直是主要的治疗手段，但是长期药物治疗引起的心血管和呼