降糖药及合并用药分析.docVIP

降糖药及合并用药分析 【摘要】 　　目的：了解我院降糖药的使用情况并作出客观分析，为临床用药提供参考。方法：随机抽取2006年含有降糖药的处方进行统计分析。结果：1152张处方中，年龄大于50岁占81.43％（938/1152），有42.27％（487/1152）伴有并发症和/或合并症，降糖药单一用药62.85％（724/1152）联合用药占37.15％（428/1152），单一用药中居前3位的分别是磺脲类，双胍类，а-葡萄糖苷酶抑制剂，联合用药中居前3位的分别是：磺脲类＋双胍类，磺脲类＋а-葡萄糖苷酶抑制剂，双胍类＋а-葡萄糖苷酶抑制剂。结论：本次调查的降糖药用药基本合理，仅少数几处存在问题，如胰岛素的使用，磺脲类药物联合应用及胃肠溃疡患者的用药等。 【关键词】 降糖药 联合用药 合理用药 　　Analysis of use of Hypoglycemic Drugs Either Alone or in Combination with Other Drugs 　　　　Abstract: Objective: To find out the situation of using of hypoglycemic drugs in our hospital and to make objective analysis,so as to provide some references for rational use of which in clinical.Method:The outpatient hypoglycemic drugs prescriptions during 2006 period were randomly collected for statistical analysis.Result:Of 1152 prescriptions,patients of 50 and over was 81.43％,42.27％（487/1152）had complications, 62.85％（724/1152）were treated with hypoglycemic drugs alone,and 37.15％（428/1152）were treated with hypoglycemic drugs in combination with other drugs. Leading the first 3 place on the list of single drug use were sulfonylureas,biguanide, а-Glycosidace Inhibitor,respectively;while leading the first 3 places on the list of drug combination were sulfonylureas in combination with biguanide, sulfonylureas in combination withа-Glycosidace Inhibitor,biguanide in combination with а-Glycosidace Inhibitor.Conclusion:The utilization of hypoglycemic drugs in our hospital was found to be basically,however,the use of drugs in a few aspects is far from perfect,such as the use of insulin,the drug combination of sulfonylureas,the choice of drugs for patients with gastrointestinal ulcer and so on. 　　Key words: Hypoglycemic drugs; Drug combination; Rational use of drugs 　　糖尿病是一种慢性代谢性疾病，可引发高血压、冠心病、高脂血症、糖尿病肾病等多种并发症，而良好的血糖控制可明显减少各种并发症的发生，降低死亡率。近年来，随着许多新型降糖药相继问世，如何根据药物的特点及患者自身状况更好地选择降糖药是临床医生面临的一个问题。本文对我院降糖药处方进行分析，了解降糖药使用情况及联合用药情况，并对降糖药使用现状进行评估，为临床用药提供参考。 　　1 资料与方法 　　随机抽取我院2006年1月至12月的门诊处方，对含有降糖药的1152